Frequency Analysis of Gradient Estimators in Volume Rendering

Gradient information is used in volume rendering to classify and color samples along a ray. In this paper, we present an analysis of the theoretically ideal gradient estimator and compare it to some commonly used gradient estimators. A new method is presented to calculate the gradient at arbitrary sample positions, using the derivative of the interpolation filter as the basis for the new gradient filter. As an example, we will discuss the use of the derivative of the cubic spline. Comparisons with several other methods are demonstrated. Computational efficiency can be realized since parts of the interpolation computation can be leveraged in the gradient estimatio

A High Power Hydrogen Target for Parity Violation Experiments

Parity-violating electron scattering measurements on hydrogen and deuterium, such as those underway at the Bates and CEBAF laboratories, require luminosities exceeding $10^{38}$cm$^{-2}$s$^{-1}$, resulting in large beam power deposition into cryogenic liquid. Such targets must be able to absorb 500 watts or more with minimal change in target density. A 40~cm long liquid hydrogen target, designed to absorb 500~watts of beam power without boiling, has been developed for the SAMPLE experiment at Bates. In recent tests with 40~$\mu$A of incident beam, no evidence was seen for density fluctuations in the target, at a sensitivity level of better than 1\%. A summary of the target design and operational experience will be presented.Comment: 13 pages, 9 postscript figure

Phases of the Traditional 505 Test: Between Session and Direction Reliability

Change of direction (COD) testing has commonly reported a single total time to quantify performance despite that tests are made up of a number of different phases. No investigation into these phases has been completed, therefore the aim of this study was to examine the reliability between sessions and directions of the different phases of a 505 test. Twenty-one male youth athletes performed the 505 test in both directions on three occasions. Differences between directions and sessions were determined via a T-test and Two-way ANOVA respectively and a significance threshold was set at P ≤ 0.05. All strategy variables show acceptable relative and absolute reliability in both directions between sessions (ICC = 0.73-0.94; CV = 2.3-6.3%) apart from ground contact time (GCT) (ICC = 0.57-0.68, CV = 14.8–22.4%). Significant differences were identified between session one and three for entry time. Significant differences between directions for exit time on day two and for full approach, entry and GCT on day three. The non-dominant turning direction showed lower relative and absolute reliability between session for entry time (ICC = 0.73 vs 0.89; CV = 6.3% vs 3.7%) and GCT (ICC = 0.57 vs 0.68; CV = 14.8% vs 22.4%). Results indicate the phases of a 505 COD test have high relative and absolute reliability between sessions, although turning directions should be considered independently

Stressed, but not defenceless: no obvious influence of irradiation levels on antifeeding and antifouling defences of tropical macroalgae

The production of defence metabolites is assumed to be costly in metabolic terms. If this holds true, low-light stress should reduce the ability of seaweeds to defend themselves chemically against herbivory and fouling. We investigated the effect of energy limitation on the defensive status of seaweeds by assessing their attractiveness to mesograzers and their activity against a bivalve macrofouler in comparison with non-stressed conspecifics. The macroalgae Codium decorticatum (Woodw.) M. Howe, Osmundaria obtusiloba (C. Agardh) R. E. Norris, Pterocladiella capillacea (S. G. Gmel.) Santel. and Hommer., Sargassum vulgare C. Agardh and Stypopodium zonale (Lamour.) Papenf. collected at the southeastern Brazilian coast were exposed to six levels of irradiation (between 1 and 180 μmol photons m−2 s−1) for 10–14 days. After this period, algae from all treatment levels were: (a) processed as artificial food and offered to an amphipod community dominated by Elasmopus brasiliensis Dana and (b) extracted to test for differences in settlement rates of the fouling mussel Perna perna L. on filter paper loaded with the crude extracts. Generally, photosynthesis rates and growth were reduced under low light conditions. Attractiveness to herbivores and macrofoulers, however, was insensitive to energy limitation. We discuss possible explanations for the observed absence of a relationship between light availability and algal defence including the change in nutritional value of the algal tissue, the allocation of resources towards defence instead of growth and the absence of costs for defence

A conflict management tool for conservation agencies

1. Growing pressure on natural resources is leading to more conservation conflicts. Governments and their statutory agencies devote increasing financial and human resources to this subject, but tend to adopt reactive, ad hoc approaches to management. 2. We combined theory and empirical data about five conservation conflicts in a transdisciplinary collaboration to co-develop a novel decision-making tool. 3. This tool uses a systematic stepwise approach with six distinct decision stages: (i) establishing whether there is a conflict or an impact; (ii) understanding the context of the conflict, including the stakeholders affected; (iii) developing shared understanding of the conflict and goals; (iv) building a consensus on how to reach the goals; (v) implementing measures; and (vi) monitoring the outcomes. 4. Policy implications. We argue this new tool has wide applicability and democratic legitimacy and offers an exciting and practical approach to improve the management of conservation conflicts

Generalized Drinfeld-Sokolov Hierarchies II: The Hamiltonian Structures

In this paper we examine the bi-Hamiltonian structure of the generalized KdV-hierarchies. We verify that both Hamiltonian structures take the form of Kirillov brackets on the Kac-Moody algebra, and that they define a coordinated system. Classical extended conformal algebras are obtained from the second Poisson bracket. In particular, we construct the $W_n^l$ algebras, first discussed for the case $n=3$ and $l=2$ by A. Polyakov and M. Bershadsky.Comment: 41 page

Quantumgroups in the Higgs Phase

In the Higgs phase we may be left with a residual finite symmetry group H of the condensate. The topological interactions between the magnetic- and electric excitations in these so-called discrete H gauge theories are completely described by the Hopf algebra or quantumgroup D(H). In 2+1 dimensional space time we may add a Chern-Simons term to such a model. This deforms the underlying Hopf algebra D(H) into a quasi-Hopf algebra by means of a 3-cocycle H. Consequently, the finite number of physically inequivalent discrete H gauge theories obtained in this way are labelled by the elements of the cohomology group H^3(H,U(1)). We briefly review the above results in these notes. Special attention is given to the Coulomb screening mechanism operational in the Higgs phase. This mechanism screens the Coulomb interactions, but not the Aharonov-Bohm interactions. (Invited talk given by Mark de Wild Propitius at `The III International Conference on Mathematical Physics, String Theory and Quantum Gravity', Alushta, Ukraine, June 13-24, 1993. To be published in Theor. Math. Phys.)Comment: 19 pages in Latex, ITFA-93-3

Primary Care Nurse Practitioner Wage Differences by Employment Setting

Background: Previous studies reported that primary care nurse practitioners working in primary care settings may earn less than those working in specialty care settings. However, few studies have examined why such wage difference exists. Purpose: This study used human capital theory to determine the degree to which the wage differences between dings PCNPs working in primary care versus specialty care settings is driven by the differences in PCNPs’ characteristics. Feasible generalized least squares regression was used to examine the wage differences for PCNPs working in primary care and specialty care settings. Methods: A cross-sectional, secondary data analysis was conducted using the restricted file of 2012 National Sample Survey of Nurse Practitioners. Findings: Oaxaca-Blinder decomposition technique was used to explore the factors contributing to wage differences. The results suggested that hourly wages of PCNPs working in primary care settings were, on average, 7.1% lower than PCNPs working in specialty care settings, holding PCNPs’ socio-demographic, human capital, and employment characteristics constant. Approximately 4% of this wage difference was explained by PCNPs’ characteristics; but 96% of these differences were due to unexplained factors. Discussion: A large, unexplained wage difference exists between PCNPs working in primary care and specialty care settings

Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin.

UNLABELLED: The macrophage response to planktonic Staphylococcus aureus involves the induction of proinflammatory microbicidal activity. However, S. aureus biofilms can interfere with these responses in part by polarizing macrophages toward an anti-inflammatory profibrotic phenotype. Here we demonstrate that conditioned medium from mature S. aureus biofilms inhibited macrophage phagocytosis and induced cytotoxicity, suggesting the involvement of a secreted factor(s). Iterative testing found the active factor(s) to be proteinaceous and partially agr-dependent. Quantitative mass spectrometry identified alpha-toxin (Hla) and leukocidin AB (LukAB) as critical molecules secreted by S. aureus biofilms that inhibit murine macrophage phagocytosis and promote cytotoxicity. A role for Hla and LukAB was confirmed by using hla and lukAB mutants, and synergy between the two toxins was demonstrated with a lukAB hla double mutant and verified by complementation. Independent confirmation of the effects of Hla and LukAB on macrophage dysfunction was demonstrated by using an isogenic strain in which Hla was constitutively expressed, an Hla antibody to block toxin activity, and purified LukAB peptide. The importance of Hla and LukAB during S. aureus biofilm formation in vivo was assessed by using a murine orthopedic implant biofilm infection model in which the lukAB hla double mutant displayed significantly lower bacterial burdens and more macrophage infiltrates than each single mutant. Collectively, these findings reveal a critical synergistic role for Hla and LukAB in promoting macrophage dysfunction and facilitating S. aureus biofilm development in vivo. IMPORTANCE: Staphylococcus aureus has a propensity to form multicellular communities known as biofilms. While growing in a biofilm, S. aureus displays increased tolerance to nutrient deprivation, antibiotic insult, and even host immune challenge. Previous studies have shown that S. aureus biofilms thwart host immunity in part by preventing macrophage phagocytosis. It remained unclear whether this was influenced solely by the considerable size of biofilms or whether molecules were also actively secreted to circumvent macrophage-mediated phagocytosis. This is the first report to demonstrate that S. aureus biofilms inhibit macrophage phagocytosis and induce macrophage death through the combined action of leukocidin AB and alpha-toxin. Loss of leukocidin AB and alpha-toxin expression resulted in enhanced S. aureus biofilm clearance in a mouse model of orthopedic implant infection, suggesting that these toxins could be targeted therapeutically to facilitate biofilm clearance in humans

The Deceleration Deficit: A Novel Field-Based Method to Quantify Deceleration During Change of Direction Performance

The study investigated the relationship between linear and change of direction (COD) speed performance components and the individual differences between deceleration deficit (DD) and COD deficit (CODD). Thirty-six subjects (mean ±SD: age = 20.3 ± 2.9 years; stature = 175.2 ± 7.7 cm; body mass = 78.0 ± 16.7 kg) completed three trials of a 505 test in both turning directions (dominant (D); non-dominant (ND)) and three 15m linear sprints. DD was calculated via the 15m approach in the 505 test, minus the athlete’s linear 15m sprint time. To compare individuals CODD and DD, z-scores were calculated, and moderate worthwhile changes (MWC) were identified between these deficit z-scores. Significant correlations were identified between linear sprints and 505 time (D: r = 0.71, 0.74; P < 0.01. ND: r = 0.76, 0.75; P < 0.01) for 10m and 15m sprint respectively, and between 505 performance and CODD (D: r = 0.74; P < 0.01. ND: r = 0.77; P < 0.01) and DD (D: r = 0.41, P < 0.05. ND: r = 0.44, P < 0.01). DD was significantly related to CODD (D: r = 0.59; P < 0.01. ND: r = 0.62; P < 0.01); however, 78% of subjects demonstrated differences between these deficit measures greater than an MWC. In conclusion, linear speed has the strongest significant relationship with 505 performance. DD could provide a more isolated construct than CODD which may be related to an athlete’s deceleration capabilities