Ротавирусная инфекция у детей — нерешенная проблема. Обзор рекомендаций по вакцинопрофилактике

These clinical guidelines were developed by the professional association of pediatric specialists «Union of Pediatricians of Russia» and approved by the Association’s Executive Committee at the Congress of Pediatricians of Russia «Actual Problems of Pediatrics». Clinical guidelines are devoted to the problem of rotavirus infection, the relevance of which is determined by the high prevalence level and significant contribution of infectious diarrhea to the mortality pattern of children in the first 5 years of life. We present epidemiological data and detailed information on the infectious agent and pathogenesis of rotavirus infection progression. A detailed picture of clinical manifestations as well as extraintestinal complications is presented. The approach to specific prophylaxis has been reasoned. Practical recommendations for immunization as well as various regimens for administering the vaccine, depending on the age and condition of the patient, are given.Данные клинические рекомендации разработаны профессиональной ассоциацией детских специалистов «Союз педиатров России» и утверждены Исполкомом ассоциации на Съезде педиатров России «Актуальные проблемы педиатрии». Клинические рекомендации посвящены проблеме ротавирусной инфекции, актуальность которой определяется высоким уровнем распространенности и значительным вкладом инфекционной диареи в структуру смертности детей первых 5 лет жизни. Приводятся эпидемиологические данные, подробно описаны особенности возбудителя, патогенез развития ротавирусной инфекции. Представлена развернутая картина клинических проявлений, а также внекишечных осложнений. Обоснована тактика специфической профилактики. Даны практические рекомендации по проведению иммунизации, а также различные схемы введения вакцины в зависимости от возраста и состояния пациента

Rotavirus Infection in Children is an Unsolved Problem. Review of Guidelines for Vaccinal Prevention

These clinical guidelines were developed by the professional association of pediatric specialists «Union of Pediatricians of Russia» and approved by the Association’s Executive Committee at the Congress of Pediatricians of Russia «Actual Problems of Pediatrics». Clinical guidelines are devoted to the problem of rotavirus infection, the relevance of which is determined by the high prevalence level and significant contribution of infectious diarrhea to the mortality pattern of children in the first 5 years of life. We present epidemiological data and detailed information on the infectious agent and pathogenesis of rotavirus infection progression. A detailed picture of clinical manifestations as well as extraintestinal complications is presented. The approach to specific prophylaxis has been reasoned. Practical recommendations for immunization as well as various regimens for administering the vaccine, depending on the age and condition of the patient, are given