1 research outputs found
Variability in Disinfection Resistance between Currently Circulating <i>Enterovirus B</i> Serotypes and Strains
The
susceptibility of waterborne viruses to disinfection is known
to vary between viruses and even between closely related strains,
yet the extent of this variation is not known. Here, different enteroviruses
(six strains of coxsackievirus B5, two strains of coxsackievirus B4
and one strain of coxackievirus B1) were isolated from wastewater
and inactivated by UV<sub>254</sub>, sunlight, free chlorine (FC),
chlorine dioxide (ClO<sub>2</sub>), and heat. Inactivation kinetics
of these isolates were compared with those of laboratory enterovirus
strains (CVB5 Faulkner and echovirus 11 Gregory) and MS2 bacteriophage.
FC exhibited the greatest (10-fold) variability in inactivation kinetics
between different strains, whereas inactivation by UV<sub>254</sub> differed only subtly. The variability in inactivation kinetics was
greater between serotypes than it was among the seven strains of the
CVB5 serotype. MS2 was a conservative surrogate of enterovirus inactivation
by UV<sub>254</sub>, sunlight, or heat but frequently underestimated
the disinfection requirements for FC and ClO<sub>2</sub>. Similarly,
laboratory strains did not always reflect the inactivation behavior
of the environmental isolates. Overall, there was considerable variability
in inactivation kinetics among and within enteroviruses serotypes,
as well as between laboratory and environmental isolates. We therefore
recommend that future disinfection studies include a variety of serotypes
and environmental isolates