Locally advanced basosquamous carcinoma: Our experience with sonidegib

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Acne and diet: a review

Acne is one of the most frequent dermatological afflictions especially for people in their first 30 years of age. Several studies have shown that nutrition is one of the key factors involved in acne pathogenesis. Data show that a high glycemic index diet may be a trigger in acne pathogenesis, while patients with a low glycemic index diet have fewer acne lesions. Milk and chocolate are also involved in the exacerbation of acne. However, foods rich in omega-3 fatty acids suppress the production of inflammatory cytokines with therapeutic effect. Additionally, docosapentaenoic acid and gamma-linolenic acid have demonstrated improved acne lesions. The aim of this review was to summarize current knowledge on the association between acne and diet with special attention to the most frequently discussed factors involved in its pathogenesis: milk, chocolate, omega-3 fatty acids, hyperglycemia, hyperinsulinism, and IGF-1

Reflectance confocal microscopy-guided microbiopsies for targeted molecular analysis

Skin biopsies for histopathology examination are generally expected to provide definitive diagnosis for cutaneous lesions. Histopathology is currently accepted as the gold standard; however, sampling errors can arise with consequent reduction of the diagnostic accuracy. Moreover, procedural obstacles and, sometimes, readers personal limitations can significantly influence the histopathology diagnosis as with every other morphological assessment approach

Reflectance confocal microscopy-guided microbiopsies for targeted molecular analysis

Skin biopsies for histopathology examination are generally expected to provide definitive diagnosis for cutaneous lesions. Histopathology is currently accepted as the gold standard; however, sampling errors can arise with consequent reduction of the diagnostic accuracy. Moreover, procedural obstacles and, sometimes, readers personal limitations can significantly influence the histopathology diagnosis as with every other morphological assessment approach

Obligate and facultative paraneoplastic dermatoses: an overview

Dermatological paraneoplastic syndromes are a group of cutaneous diseases associated with malignancy, but not directly related to the primary tumor itself or to its metastases. It is of utmost importance for the dermatologist to recognize the major cutaneous paraneoplastic syndromes to diagnose the underlying tumors that trigger them as early as possible. In this overview, skin conditions that are highly correlated with malignancy, whose recognition implies a mandatory investigation of internal cancer, are described