5 research outputs found

    Scatter plot for lactate and the lactate-to-pyruvate ratio.

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    <p>The entire dataset is divided in the four patterns described in the text. We propose the following terminology for the four patterns: Pattern 1 (normal metabolism), Pattern 2 (aerobic hyperglycolysis), Pattern 3 (anaerobic metabolism), and Pattern 4 (low pyruvate). For an explanation, see the text.</p

    Scatter plot of the relationship between lactate and the lactate-to-pyruvate ratio.

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    <p>The best-fit straight line using an ordinary least squares method is included. In this plot, outliers with a lactate-to-pyruvate ratio >150 were excluded. The plotted residuals and other regression diagnostics show that the relationships between lactate and the lactate-to-pyruvate ratio could not be adequately modeled by any linear or non-linear model.</p

    Box-and-whisker plots summarizing the distribution of data for glucose, lactate, and pyruvate.

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    <p>The rectangular box spans the first to the third quartile of data and the median, marked in the center of the box, is labeled with its value to the right. Whiskers extend to the furthest observations within ±150% of the interquartile range. Observations outside 150% of the interquartile range are marked as outliers with dots. N = 5305 represents all valid matched data for the three variables. All variables were highly skewed to the right. For an explanation, see the text in the results section.</p
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