Two Catalytic Methods of an Asymmetric Wittig [2,3]-Rearrangement

Two different approaches for asymmetric catalytic Wittig [2,3]-rearrangement were developed. Allyloxymalonate derivatives were converted into homoallyl alcohols via organocatalytic or Ca²⁺-catalyzed pathways in moderate to high enantioselectivities

Asymmetric Organocatalytic Wittig [2,3]-Rearrangement of Oxindoles

A highly enantioselective organocatalytic [2,3]-rearrangement of oxindole derivatives is presented. The reaction was catalyzed by squaramide, and this provides access to 3-hydroxy 3-substituted oxindoles in high enantiomeric purities