Dialogue avec l'oeuvre ravagee

Au terme de carrieres consacrees a l'examen et a la restauration des chefs-d'oeuvre du patrimoine national deux specialistes un historien de l'art et un microchimiste se sont penches sur les problemes de la conservation une matiere combien complexe inepuisable et controversee depuis bientot trois siecles. Leur ouvrage n'est ni un atlas de la pathologie des tableaux et des sculptures ni un livre de recettes ni un manuel qui explique en detail les etapes d'un certain nombre d'interventions visant a restaurer les oeuvres. Il propose une reflexion sur le fond du probleme a la lumiere de la pratique de l'atelier de restauration et celle des acquis de laboratoire. Et ce en dehors des clans et des ecoles loin des connivences. Les auteurs essaient d'evaluer le sens et le non-sens des interventions qu'on estime pouvoir imposer aux oeuvres. Ils invitent a ecouter l'oeuvre. Et de quoi nous parlent les images ravagees? Des oeuvres intactes de la beaute de l'ephemere sans oublier le comportement etonnant des hommes envers ce qu'ils ont cree de meilleur

Vitamin D deficiency, depression course and mortality: Longitudinal results from the Netherlands Study on Depression in Older persons (NESDO)

Item does not contain fulltextOBJECTIVE: To study the effect of vitamin D levels on depression course and remission status after two years, as well as attrition and mortality, in an older cohort. METHODS: This study was part of the Netherlands Study on Depression in Older persons (NESDO), a prospective cohort study. 367 depressed older persons (>/=60years) were included. Baseline vitamin D status, reasons for loss to follow up, clinical depression diagnosis at two-year follow up, and six-monthly symptom scores were obtained. Data were analyzed by logistic regression and random coefficient models and adjusted for confounders of vitamin D status. Results : Vitamin D had no effect on the course of depression or remission, except for a trend towards lower remission rates in the severely deficient subgroup (25-(OH) vitamin D<25nmol/l). Patients who died during follow up had significantly lower 25-(OH) vitamin D and 1,25-(OH)2 vitamin D levels than patients with continued participation. CONCLUSIONS: For the total sample we found no effect of vitamin D levels on the course of depression or remission rates. However, we did find an effect of lower vitamin D levels on mortality. This strengthens the interpretation of vitamin D deficiency being a marker for poor somatic health status. The trend towards lower remission rates in the severely deficient subgroup raises the question whether this group could benefit from supplementation. Randomized controlled trials are necessary to study this