Ranking of vaccine-preventable diseases by disease burden at population/individual level in the Netherlands in 2007–2011.

<p>Diphtheria and poliomyelitis could not be included because there were no cases reported in this period. The area of each bubble is proportional to the average number of estimated annual cases (50 cases were added to each bubble for visibility reasons). Both axes are on a logarithmic scale. (DALY = Disability-Adjusted Life Years, population level = number of DALYs/year, individual level = number of DALYs/100 infections, I. = invasive).</p

Ranking of food-related diseases by disease burden at population/individual level in the Netherlands in 2007–2011.

<p>The area of each bubble is proportional to the average number of estimated annual cases (200 cases were added to each bubble for visibility reasons). Both axes are on a logarithmic scale. (DALY = Disability-Adjusted Life Years, population level = number of DALYs/year, individual level = number of DALYs/100 infections).</p

Average annual disease burden in the Netherlands in 2007–2011 for new cases of sexually-transmitted infections.

<p>YLD and YLL components are shown separately. Red lines indicate 95% uncertainty intervals.(DALY = Disability-Adjusted Life Year, YLD = Years Lived with Disability, YLL = Years of Life Lost).</p

Estimated annual disease burden in the period 2007–2011 for <i>new</i> cases of sexually-transmitted infections, vaccine-preventable diseases, food-related diseases, and respiratory diseases: mean (with 95% uncertainty intervals) YLD/year, YLL/year, DALYs/year, and DALYs/100 infections.

<p>Estimated annual disease burden in the period 2007–2011 for <i>new</i> cases of sexually-transmitted infections, vaccine-preventable diseases, food-related diseases, and respiratory diseases: mean (with 95% uncertainty intervals) YLD/year, YLL/year, DALYs/year, and DALYs/100 infections.</p

Average annual disease burden in the Netherlands in 2007–2011 for new cases of vaccine-preventable diseases.

<p>YLD and YLL components are shown separately. Red lines indicate 95% uncertainty intervals. (DALY = Disability-Adjusted Life Year, YLD = Years Lived with Disability, YLL = Years of Life Lost, I. = invasive).</p

Average annual disease burden in the Netherlands in 2007–2011 for new cases of respiratory diseases.

<p>YLD and YLL components are shown separately. Red lines indicate 95% uncertainty intervals. (DALY = Disability-Adjusted Life Year, YLD = Years Lived with Disability, YLL = Years of Life Lost).</p

Ranking of respiratory diseases by disease burden at population/individual level in the Netherlands in 2007–2011.

<p>The area of each bubble is proportional to the average number of estimated annual cases. Both axes are on a logarithmic scale. (DALY = Disability-Adjusted Life Years, population level = number of DALYs/year, individual level = number of DALYs/100 infections).</p

Ranking of sexually-transmitted infections by disease burden at population/individual level in the Netherlands in 2007–2011.

<p>The area of each bubble is proportional to the average number of estimated annual cases. Both axes are on a logarithmic scale.(DALY = Disability-Adjusted Life Years, population level = number of DALYs/year, individual level = number of DALYs/100 infections).</p

Total number of <i>new</i> cases in 2007–2011 in the Netherlands, multiplication factors (MFs) chosen to adjust for under-estimation, and the estimated annual number of total infections and deaths (averaged over the period 2007–2011 and adjusted for under-estimation and the proportion symptomatic), per disease.

<p>Total number of <i>new</i> cases in 2007–2011 in the Netherlands, multiplication factors (MFs) chosen to adjust for under-estimation, and the estimated annual number of total infections and deaths (averaged over the period 2007–2011 and adjusted for under-estimation and the proportion symptomatic), per disease.</p

Preliminary estimates of the burden of disease in terms of DALYs per 100,000 individuals per year for selected infections in four European countries.

<p>The differences seen between countries (A–D) may be due to differences in surveillance and/or to differences in the (distribution of) incidence of infections in populations. STEC/VTEC, shigatoxin-producing <i>Escherichia coli</i>/verocytotoxin-producing <i>E. coli</i>; YLD, number of life years lost due to disability; YLL, number of life years lost due to premature death.</p