11 research outputs found
TCT-317 Systematic detection of coronary vasospasm by methylergonovine-based provocative test in 2,397 patients
TCT-77 Safety of provocative tests to detect coronary artery spasm. Results from a French registry including 2,430 patients.
TCT-609 Incidence, diagnosis and clinical outcomes of patients with impaired coronary vasoreactivity: insights from a protocol of systematic coronary artery spasm detection over ten years.
Clinical Survey of Dengue Virus Circulation in the Republic of Djibouti between 2011 and 2014 Identifies Serotype 3 Epidemic and Recommends Clinical Diagnosis Guidelines for Resource Limited Settings.
Dengue virus is endemic globally, throughout tropical and sub-tropical regions. While the number of epidemics due to the four DENV serotypes is pronounced in East Africa, the total number of cases reported in Africa (16 million infections) remained at low levels compared to Asia (70 million infections). The French Armed forces Health Service provides epidemiological surveillance support in the Republic of Djibouti through the Bouffard Military hospital. Between 2011 and 2014, clinical and biological data of suspected dengue syndromes were collected at the Bouffard Military hospital and analyzed to improve Dengue clinical diagnosis and evaluate its circulation in East Africa. Examining samples from patients that presented one or more Dengue-like symptoms the study evidenced 128 Dengue cases among 354 suspected cases (36.2% of the non-malarial Dengue-like syndromes). It also demonstrated the circulation of serotypes 1 and 2 and reports the first epidemic of serotype 3 infections in Djibouti which was found in all of the hospitalized patients in this study. Based on these results we have determined that screening for Malaria and the presence of the arthralgia, gastro-intestinal symptoms and lymphopenia < 1,000cell/ mm3 allows for negative predictive value and specificity of diagnosis in isolated areas superior to 80% up to day 6. This study also provides evidence for an epidemic of Dengue virus serotype 3 previously not detected in Djibouti
Number of cases of Dengue virus serotypes from December 2011 to May 2014 by month.
<p>Blue bars represented serotype 1, red bars the serotype 2 and green bars serotype 3.</p
Clinical signs and symptoms according to Dengue diagnosis (Dengue positive vs Dengue negative patients)—Results of univariate and multivariate analyses.
<p>p-values were obtained using likelihood ratio tests.</p
Suspected and confirmed cases of Dengue from January 2011 to May 2014 by month.
<p>Suspected cases are represented in blue and confirmed cases in red.</p
Lymphocyte and platelet median counts in DENV-POS and DENV-NEG patients and according to DENV serotype among DENV-POS patients.
<p>IQ: InterQuartil interval</p
Clinical signs observed for each serotype of Dengue virus.
<p>Blue bars represented serotype 1, red bars serotype 2 and green bars serotype 3.</p