1,275 research outputs found

    An Alien Foundation : The Eclectism of Antonin Dvorak\u27s American Period

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    In 1891 Bohemian composer Antonin Dvorak (1841-1904) was offered a position as the Director of the American Conservatory in New York City by Jeanette Thurber (1850-1946) due to his reputation as a nationalistic composer. Thurber was intending to create a national music for America and hired Dvorak to not only promote the American Conservatory, but help her achieve her goal of an American style. By early 1892 an agreement was reached between the two parties, and Dvorak assumed his role as Director of the Conservatory in October of 1892, a tenure which lasted until May 1895. This three year period, identified as Dvorak\u27s American period, has ignited debate over his identification of source materials for composers to utilize as a possible source of influences to create an American nationalistic style of compositions. Based on Dvorak\u27s public writings during this periods, one might conclude that Negro Spirituals and music of Native Americans should form the basis of an American nationalistic style, but practice Dvorak\u27s compositions suggests a different direction entirely. Indeed previous scholars who have examined Dvorak\u27s American works have reached no consensus regarding the extent of influence that Negro Spirituals and Native American music in these works. In this paper I will suggest an alternative to the influence of the Negro Spiritual and Native American music on the creation of Dvorak\u27s American period, and assert that it was, in fact, the influence of the Indianist and Progressive Movements that helped shape the music to invoke Americaness. I will support my hypothesis through a comparison of indigenous idioms, an examination of contract issues between Thurber and Dvorak, and contradictions between letters written by the composer to family and friends and the newspaper editorials attributed to Dvorak

    Pain Management in Cancer Center Inpatients:A Cluster Randomized Trial to Evaluate a Systematic Integrated Approach—The Edinburgh Pain Assessment and Management Tool

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    Purpose Pain is suboptimally managed in patients with cancer. We aimed to compare the effect of a policy of adding a clinician-delivered bedside pain assessment and management tool (Edinburgh Pain Assessment and management Tool [EPAT]) to usual care (UC) versus UC alone on pain outcomes. Patients and Methods In a two-arm, parallel group, cluster randomized (1:1) trial, we observed pain outcomes in 19 cancer centers in the United Kingdom and then randomly assigned the centers to either implement EPAT or to continue UC. The primary outcome was change in the percentage of study participants in each center with a clinically significant (≥ 2 point) improvement in worst pain (using the Brief Pain Inventory Short Form) from admission to 3 to 5 days after admission. Secondary outcomes included quality of analgesic prescribing and opioid-related adverse effects. Results Ten centers were randomly assigned to EPAT, and nine were assigned to UC. We enrolled 1,921 patients and obtained outcome data from 93% (n = 1,795). Participants (mean age, 60 years; 49% women) had a variety of cancer types. For centers randomly assigned to EPAT, the percentage of participants with a clinically significant improvement in worst pain increased from 47.7% to 54.1%, and for those randomly assigned to continue UC, this percentage decreased from 50.6% to 46.4%. The absolute difference was 10.7% (95% CI, 0.2% to 21.1%; P = .046) and it increased to 15.4% (95% CI, 5.8% to 25.0%; P = .004) when two centers that failed to implement EPAT were excluded. EPAT centers had greater improvements in prescribing practice and in the Brief Pain Inventory Short Form pain subscale score. Other pain and distress outcomes and opioid adverse effects did not differ between EPAT and UC. Conclusion A systematic integrated approach improves pain outcomes for inpatients in cancer centers without increasing opioid adverse effects

    Pain in malignant pleural mesothelioma: a prospective characterisation study.

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    INTRODUCTION: Malignant pleural mesothelioma (MPM) is associated with severe pain. The underlying neurobiology of this is complex. The primary aim of this study was to characterize pain in MPM. METHODS: This study was undertaken as part of a trial examining radiotherapy for the treatment of pain in MPM (ISRCTN 10644347). Patients had MPM with associated pain for which radiotherapy was planned and a worst pain score ≥ 4/10. The following assessments were undertaken: clinical neuropathic pain assessment, Brief Pain Inventory (BPI), Leeds Assessment of Neuropathic Symptoms and Signs (LANSS), Short form of the McGill Pain Questionnaire (SF-MPQ), and Quantitative Sensory Testing (QST). The relationship of these characteristics and response to radiotherapy was assessed. Unless stated, medians and interquartile range (IQR) are used. RESULTS: Thirty-seven patients were recruited. Average pain and worst pain was 4 (4-6) and 8 (6-8), respectively. Higher average pain and higher worst pain scores were associated with higher interference scores on the BPI, P < 0.001 and P < 0.0005. Twenty patients (54%) had a clinical diagnosis of neuropathic pain, and of these, only six patients (40%) screened positively for neuropathic pain using the LANSS. Patients with a high LANSS also had higher BPI and SF-MPQs. The presence of neuropathic pain (clinically or by LANSS) did not predict response to radiotherapy, P < 0.05. The SF-MPQ scores were higher in those with abnormal cool sensation on QST (P = 0.016). CONCLUSION: Pain in mesothelioma varies among patients and may have neuropathic components. An adequate pain assessment is necessary to guide the clinician in the appropriate choice of analgesics
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