Cervicovaginal (a) and anorectal (b) <i>Chlamydia trachomatis</i> rRNA and DNA detection between 23 and 51 days post directly observed Azythromycin treatment.

<p>Each row represents a cervicovaginal or anorectal Ct infection. Twenty five infections (out of 59) had at least one positive sample between 23 and 51 days post-treatment and these 25 infections are displayed here. Self taken swabs were tested for Ct rRNA (TMA, Tigris; GenProbe, San Diego, US) and plasmid DNA (real-time in house PCR; Amsterdam, the Netherlands) <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034108#pone.0034108-Catsburg1" target="_blank">[12]</a>.</p

Test results of DBS-serum pairs of the validation study.

<p>Test results of DBS-serum pairs of the validation study.</p

Subgroup analysis of DBS-serum pairs in HIV positive participants.

<p>Subgroup analysis of DBS-serum pairs in HIV positive participants.</p

Association (odds ratio and 95% confidence interval) between genital HPV DNA and HPV-specific antibody genotypes, for women and MSW.

<p>Ab = antibody; OR = odds ratio; CI = confidence interval; MSW = men who have sex with women only.</p

Positivity rate for genital and anal DNA detection in women, MSW and MSM.

<p>Black gives the positivity rate for persons with a HPV DNA detection only at the genitals, dark grey gives the positivity rate for persons with an HPV DNA infection genital as well as anal, and light grey are the positivity rates when persons are only detected with HPV DNA anally. The figures includes women (N = 118), MSW (N = 56) and MSM (N = 124) of whom a genital and an anal sample were available. MSW =  men who have sex with women only; MSM = men who have sex with men.</p

Scatterplots of the index values measured in DBS and serum.

<p>Scatterplots of the index values measured in DBS and serum. 2a. shows the log transformed results for HIV Ag/Ab, 2b. the results for <i>T</i>. <i>pallidum</i> Ig 2c. the log transformed results for HBsAg.</p

Past and current (ano)genital chlamydia and gonorrhea infections: women, MSW, and MSM.

<p>MSM = men who have sex with men; MSW = men who have sex with women only.</p

Adjusted odds ratio and 95% confidence interval for the detection of genital and anal HPV DNA and HPV antibodies using multilevel analyses (generalized estimating equations [GEE)]) in men who have sex with men (MSM).

<p>The following variables were included into the crude GEE model: age, ethnicity, years sexually active, number of lifetime sex partners, number of sex partners in the last six months, condom use in the last six months with a steady partner, condom use in the last six months with a casual partner, a chlamydia or gonorrhea in the past, a current urogenital chlamydia infection, a current anal chlamydia or gonorrhea infection, passive anal intercourse in the past six months, and the seven different HPV genotypes.</p>*<p>The model for genital HPV DNA could not be run for MSM due to small numbers.</p><p>AOR = adjusted odds ratio; CI = confidence interval; NI  =  not included in the multivariable model; NS  =  not significant in multivariable model.</p

Genital (and anal) HPV DNA and HPV-specific antibody seropositivity in women, MSW, and MSM.

<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0060696#pone-0060696-g002" target="_blank">Figure 2a–c</a> gives the genital HPV DNA (light grey), HPV-specific antibody seropositivity (dark grey), as well as the percentage of persons detected with genital HPV DNA as well as HPV antibodies (black) with 95% confidence intervals in women (N = 2233), MSW (N = 922), and MSM (N = 173) per HPV genotype. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0060696#pone-0060696-g002" target="_blank">Figure 2d</a> gives the anal HPV DNA (light grey), HPV-specific antibody seropositivity (dark grey) as well as the percentage of persons detected with anal HPV DNA as well as HPV antibodies (black) with 95% confidence intervals in MSM (N = 124). Ab = antibody; MSM = men who have sex with men; MSW = men who have sex with women only.</p

Adjusted odds ratio and 95% confidence interval for the detection of genital and anal HPV DNA and HPV antibodies using multilevel analyses (generalized estimating equations [GEE)]) in men who have sex with women only (MSW).

<p>The following variables were included into the crude GEE model: age, ethnicity, years sexually active, number of lifetime sex partners, number of sex partners in the last six months, condom use in the last six months with a steady partner, condom use in the last six months with a casual partner, a chlamydia or gonorrhea in the past, a current urogenital chlamydia infection, passive anal intercourse in the past six months, and the seven different HPV genotypes.</p>*<p>The model for anal HPV DNA could not be run for MSW due to small numbers.</p><p>AOR = adjusted odds ratio; CI = confidence interval; NI  =  not included in the multivariable model; NS  =  not significant in multivariable model.</p