A personal journey through coronavirus evolution

For companion animal medicine, Feline Infectious Peritonitis (FIP) is an important disease - it is fatal, and prevention is a challenge. FIP is a sporadic viral condition - a contradiction in terms. The explanation: mutants of a coronavirus (CoV) that is endemic in most feline populations, arise in individual cats, change their tropism from enterocyte to macrophage and cause a polyserositis with pyogranulomas. The FIP causing variants are usually not transmitted, and there is no epidemic spread.PowerPoint presentation and curriculum vitae of Prof Marian C. Horzinek. This Arnold Theiler Memorial Lecture was delivered on September 5, 2013 at the University of Pretoria, Faculty of Veterinary Medicine, Onderstepoort. Marian C. Horzinek is Professor Emeritus of Virology and Viral Diseases of the Faculty of Veterinary Medicine, Utrecht University and former Director of the Graduate School of Animal Health, Utrecht University.ab201

World Small Animal Veterinary Association Vaccination Guidelines Group: vaccination guidelines for cats and dogs pictorial factsheets 2015

Pictorial fact sheet describing symptomatic presentation and guidelines for vaccination of cats and dogs for Canine Distemper Virus, Canine Adenovirus-1, Canine Parvovirus, Feline Parvovirus, Feline Herpesvirus, Feline Calicivirus and Rabies Virus

Incidence of Feline lmmunodeficiency virus reactive antibodies in free-ranging lions of the Kruger National Park and the Etosha National Park in southern Africa detected by recombinant FIV p24 antigen

Lion sera from the Kruger National Park (KNP) dating back to 1977 and from the Etosha National Park (ENP), obtained from 1989 to 1991 , have been analysed by ELISA and Western blot analyses using a genetically engineered antigen representing the p24 structural protein of feline immunodeficiency virus (FIV). It was concluded that some 83% of 98 KNP lion sera reacted with the p24 antigen, while none of 28 ENP lion sera reacted. A few other KNP felids (cheetahs and genets) gave samples that did not react with the FIV p24 antigen. For the KNP lions, apart from a lower prevalence in cubs (50%), no particular trends were demonstrated in terms of age, sex, date or origins of the samples. In Western blot and radio-immunoprecipitation analyses the lion sera reacted with the engineered p24 antigen, as well as with the p15 and p24 gag proteins and the p50 gag precursor protein from FIV, indicating that the agent is probably a lentivirus related to FIV. The ELISA with the engineered p24 antigen required less serum and appears to be more sensitive at detecting FlY-reactive antibodies than assays with available commercial kits.The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.Virbac Laboratories, France.mn201

Something old, someting new : Update of the 2009 and 2013 ABCD guidelines on prevention and management of feline infectious diseases

OVERVIEW: The ABCD has published 34 guidelines in two Special Issues of the Journal of Feline Medicine and Surgery (JFMS): the first in July 2009 (Volume 11, Issue 7, pages 527-620) and the second in July 2013 (Volume 15, Issue 7, pages 528-652). The present article contains updates and new information on 18 of these (17 disease guidelines and one special article 'Prevention of infectious diseases in cat shelters'). For detailed information, readers are referred to the guidelines published in the above-mentioned JFMS Special Issues