Individual renal function biomarkers of the dogs under study before (at day 0) and after (at day 28) treatment with marbofloxacin.

<p>Individual renal function biomarkers of the dogs under study before (at day 0) and after (at day 28) treatment with marbofloxacin.</p

Concentrations of plasma creatinine (A), plasma urea (B) and urine protein to creatinine (UPC) ratio (C) on days 0, 7, 14, 21 and 28 of treatment with marbofloxacin in the dogs under study.

<p>Values are expressed as the mean±standard deviation.</p

Principal components analysis plot.

<p><b>Interrelation between the main parameters studied at day 0 (A) and at day 28 (B)</b>. Alb: albumin; AbTiter: antibody titer; Crea: creatinine; CScore: clinical score; DBP: diastolic blood pressure; Glob: globulins; P: phosphate; ParLoad: parasitic load; PCV: packed cell volume; SBP: systolic blood pressure; UCystatin: urine cystatin C; UFerritin: urine ferritin; UPC: urine protein to creatinine ratio.</p

Haematological and biochemical parameters of 28 dogs with leishmaniasis and CKD before (at day 0) and after treatment (at day 28).

<p>Haematological and biochemical parameters of 28 dogs with leishmaniasis and CKD before (at day 0) and after treatment (at day 28).</p

Blood pressure measurement on days 0, 7, 14, 21 and 28 of treatment with marbofloxacin in the dogs under study.

<p>Values are expressed as the mean±standard deviation. ^a<i>p</i><0.02 vs day 0, ^b<i>p</i><0.02 vs day 7.</p

Individual clinical score, antibody titers and parasitic load of the dogs under study before (at day 0) and after (at day 28) treatment with marbofloxacin.

<p>Individual clinical score, antibody titers and parasitic load of the dogs under study before (at day 0) and after (at day 28) treatment with marbofloxacin.</p