Resistin Preferentially Induces Inflammatory Markers in Human WAT.

<div><p>Human WAT explants were incubated with 10 ng/ml TNF, white bars, or 50 ng/ml resistin, grey bars, for 24 hrs and the fold change for several markers assessed by comparison with their level in basal cultures after 24 hrs.</p> <p>In <b><i>A</i></b> both gene (left) and protein (right) expressions of proinflammatory cytokines are shown, while <b><i>B</i></b> represents other inflammation-related effects in WAT.</p> <p> <b><i>C</i></b> demonstrates different effects of TNF and resistin on markers of adipocyte differentiation. *, <i>P</i><0.1; **, <i>P</i><0.01; ***, <i>P</i><0.001.</p></div

Correlation between serum resistin levels and age in systemic lupus erythematosus (SLE) patients and controls

The constant and the regression coefficients, with respect to resistin values and age, were compared with the corresponding parameters of the controls by use of a special test. The regression coefficient is the slope. No significant difference was found between these parameters.<p><b>Copyright information:</b></p><p>Taken from "Role of resistin as a marker of inflammation in systemic lupus erythematosus"</p><p>http://arthritis-research.com/content/10/1/R15</p><p>Arthritis Research & Therapy 2008;10(1):R15-R15.</p><p>Published online 30 Jan 2008</p><p>PMCID:PMC2374439.</p><p></p

Figure 2

<p>A. Balb/C mouse knee joint 30 days following intra-articular transfer of cells overexpressing Flt3-L. Arrows indicate bone erosions. Abbreviations: C = cartilage, M = meniscus, S = synovitis. B. Balb/C mouse knee joint 30 days following intra-articular transfer of cells not overexpressing Flt3-L. Abbreviations: C = cartilage, JC = joint cavity, M = meniscus, ST = synovial tissue.</p

Clinical data regarding 130 RA-patients and 103 controls participating in the study.

*<p>N.A. = not analyzed.</p

Flt3-L levels in synovial fluids and sera of RA patients and of control subjects.

<p>Median displayed in the horizontal line. RA serum (n = 130, median 80, range (min 0–max 3320), RA SF (n = 130, median 160 pg/ml, range (min 20–max 1980), control subjects serum (n = 70, median 70.5 pg/ml, range (min 0–max 160), and control subjects SF (n = 37, median 120 pg/ml, range (min 0–max 360).</p