THE DEVELOPMENT OF THE BEARER FOR THE AFFINE CHROMATOGRAPHY AND CREATION OF THE SORBENT FOR CLEANING THE INTERFERON

The purpose of the work: creating the technological bearer for the affine czromatography and obtaining the immunoaffine sorbent on its base for cleaning the interferon and the sorbent for the quantitative determination of the man's glycohemoglobin. Determined have been the conditions, ensuring the high specific capacity, the improved hydrodynamic properties and the high stability of the affine sorbents. The new bearer for the affine chromatography, the immunoaffine sorbent for cleaning the interferon and sorbent with the immobilized m-aminophenylboron acid for the quantitative determination of the man's glycohemoglobin, have been obtained. The new immunoaffine sorbent has been included in the production schedule of the interferon receiving, the sorbent is being used in the INTERKOR enterprise. The capacity of the immunoaffine cleaning of interferon has been increased by 5 times. The field of application: the production of medical preparations of interferon, the laboratory diagnostics of the diabethesAvailable from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio

Numerical Simulation Study of Huff-n-Puff Hydrocarbon Gas Injection Parameters for Enhanced Shale Oil Recovery

Gas injection has already proven to be an efficient shale oil recovery method successfully tested all around the world. However, gas-enhanced oil recovery methods have never been implemented or tested for the greatest Siberian shale oil formation yet. This article proposes numerical simulation of a hydrocarbon gas injection process into a horizontal well with multiple hydraulic fractures perforating Bazhenov shale oil formation in Western Siberia characterized by ultra-low permeability. A complex field-scale numerical study of gas injection for such a formation has never been performed before and is presented for the first time in our work. The hydrodynamic compositional simulation was performed utilizing a commercial simulator. A sensitivity study for different operating parameters including cycle times, bottom-hole pressures for the production and injection period, and injected gas composition was performed after the model was history matched with the available production data. Some uncertain reservoir properties such as relative permeability curves were also sensitized upon. Two different ways of accounting for multiple hydraulic fractures in the simulation model are presented and the simulation results from both models are compared and discussed. Eventually, huff-n-puff injection of a hydrocarbon gas resulted in a 34–117% increase in oil recovery depending on the fracture model

Effects of Plant Growth Promoting Rhizobacteria on the Content of Abscisic Acid and Salt Resistance of Wheat Plants

Although salinity inhibits plant growth, application of appropriate rhizosphere bacteria can diminish this negative effect. We studied one possible mechanism that may underlie this beneficial response. Wheat plants were inoculated with Bacillus subtilis IB-22 and Pseudomonas mandelii IB-Ki14 and their consequences for growth, water relations, and concentrations of the hormone abscisic acid (ABA) were followed in the presence of soil salinity. Salinity alone increased ABA concentration in wheat leaves and roots and this was associated with decreased stomatal conductance, but also with chlorophyll loss. Bacterial treatment raised ABA concentrations in roots, suppressed accumulation of leaf ABA, decreased chlorophyll loss, and promoted leaf area and transpiration. However, water balance was maintained due to increased water uptake by inoculated plants, brought about in part by a larger root system. The effect may be the outcome of ABA action since the hormone is known to maintain root extension in stressed plants. Root ABA concentration was highest in salt-stressed plants inoculated with B. subtilis and this contributed to greater root hydraulic conductivity. We conclude that bacteria can raise salt resistance in wheat by increasing root ABA, resulting in larger root systems that can also possess enhanced hydraulic conductivity thereby supporting better-hydrated leaves

What is next for the neurobiology of temperament, personality and psychopathology?

This paper represents the outcome of a multidisciplinary discussion on what works, what does not, and what can be improved, in ongoing work on biobehavioral taxonomies and their biomarkers. The authors of this paper, representing a wide spectrum of biobehavioral disciplines (clinical, developmental, differential psychology, neurophysiology, endocrinology, psychiatry, neurochemistry, and neurosciences), have contributed more extensive opinions to the Theme Issue 'Neurobiology of temperament, personality and psychopathology: what's next?'. The authors identified 10 directions in international and multidisciplinary cooperation, and multiple insights for 'what is next' for each of these directions