53 research outputs found

    Youth Savings Patterns and Performance in Colombia, Ghana, Kenya, and Nepal: YouthSave Research Report 2015

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    If offered an opportunity to save via formal financial services, will youth in developing countries participate, save, and accumulate assets? This is one of the key questions in YouthSave, a savings initiative implemented in four developing countries, targeting youth aged 12 to 18 years, from predominantly low-income households. This report presents two-year findings from a study that tracks account uptake and saving patterns and performance in youth savings accounts in four countries: Colombia, Ghana, Kenya, and Nepal. This savings demand assessment (SDA) is ambitious in its attempt to include systematic data on as many youth savers as possible. The result is a very large dataset that enables us to report in detail who is saving, and factors associated with saving patterns and performance. The report is divided into four sections: the ten key findings; the project summary; the body, which consists of Chapters 1 through 9 and summarizes information across all four countries; and the appendices, which include country-specific details and summary tables. A summary of findings appears at the end of each chapter

    Youth Savings Patterns and Performance in Colombia, Ghana, Kenya, and Nepal: Executive Summary

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    This summary presents an overview of findings from the YouthSave Project\u27s 2015 research report Youth Savings Patterns and Performance in Columbia, Ghana, Kenya, and Nepal. Created in partnership with the MasterCard Foundation, YouthSave investigated the potential of savings accounts as a tool for youth development and financial inclusion in developing countries by co-designing tailored, sustainable savings products with local financial institutions and assessing their performance and development outcomes with local researchers. This study tracked account uptake, saving patterns, and savings performance in youth savings accounts in Colombia, Ghana, Kenya, and Nepal

    Youth Saving Patterns and Performance in Colombia, Ghana, Kenya, and Nepal: Key Findings

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    If provided an opportunity to save via formal financial services, do youth in developing countries participate, save, and accumulate assets? This was one of the key questions asked in YouthSave. Savings accounts were created in four developing countries, targeting youth aged 12 to 18 years from predominantly low-income households. This brief highlights research findings on account uptake and savings from the Savings Demand Assessment (SDA)

    UK vaccines network:Mapping priority pathogens of epidemic potential and vaccine pipeline developments

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    During the 2013–2016 Ebola outbreak in West Africa an expert panel was established on the instructions of the UK Prime Minister to identify priority pathogens for outbreak diseases that had the potential to cause future epidemics. A total of 13 priority pathogens were identified, which led to the prioritisation of spending in emerging diseases vaccine research and development from the UK. This meeting report summarises the process used to develop the UK pathogen priority list, compares it to lists generated by other organisations (World Health Organisation, National Institutes of Allergy and Infectious Diseases) and summarises clinical progress towards the development of vaccines against priority diseases. There is clear technical progress towards the development of vaccines. However, the availability of these vaccines will be dependent on sustained funding for clinical trials and the preparation of clinically acceptable manufactured material during inter-epidemic periods

    Multiple-Strain Infections of Human Cytomegalovirus with High Genomic Diversity are Common In Breast Milk from HIV-Positive Women in Zambia

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    Background In developed countries, human cytomegalovirus (HCMV) is a major pathogen in congenitally infected and immunocompromised individuals, where multiple-strain infection appears linked to disease severity. The situation is less documented in developing countries. In Zambia, breast milk is a key route for transmitting HCMV and carries higher viral loads in human immunodeficiency virus (HIV)–infected women. We investigated HCMV strain diversity. Methods High-throughput sequence datasets were generated from 28 HCMV-positive breast milk samples donated by 22 mothers (15 HIV-infected and 7 HIV-negative) at 4–16 weeks postpartum, then analyzed by genome assembly and novel motif-based genotyping in 12 hypervariable HCMV genes. Results Among the 20 samples from 14 donors (13 HIV-infected and one HIV-negative) who yielded data meeting quality thresholds, 89 of the possible 109 genotypes were detected, and multiple-strain infections involving up to 5 strains per person were apparent in 9 HIV-infected women. Strain diversity was extensive among individuals but conserved compartmentally and longitudinally within them. Genotypic linkage was maintained within hypervariable UL73/UL74 and RL12/RL13/UL1 loci for virus entry and immunomodulation, but not between genes more distant from each other. Conclusions Breast milk from HIV-infected women contains multiple HCMV strains of high genotypic complexity and thus constitutes a major source for transmitting viral diversity
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