Desempenho produtivo de porta-enxertos de macieira da série Geneva em solo de replantio

The objective of this work was to identify rootstocks with competitive agronomic potential to substitute those currently used in Southern Brazil for the Galaxy and Fuji Suprema apple scion cultivars cultivated on replanting soils. The experiment was carried out in the municipality of Lebon Regis, in the state of Santa Catarina, Brazil, from the 2009/2010 to the 2014/2015 crop season, in a randomized complete block design, with four replicates. The yield performance of the 'Galaxy' and 'Fuji Suprema' scions grafted on the G.056, G.202, G.213, G.814, G.896, G.969, M.9, and Marubakaido/M.9 rootstocks was evaluated. G.896 and G.814 stood out due to their superior annual and cumulative fruit yields, as well as to their greater yield regularity, although they showed lower ability of dwarfing the scion. The greatest average fruit weight of 'Galaxy' was obtained on G.056 and G.213. For 'Fuji Suprema', G.969 promoted smaller fruits, whereas the other rootstocks did not differ. All the evaluated rootstocks produced less suckers than Marubakaido/M.9 and less burrknots than M.9 and Marubakaido/M.9. In general, on replanting soil conditions, G.202 is promising among dwarfing rootstocks, mainly for 'Fuji Suprema'. G.056, G.814, and G.896 also stand out, and the two first are more specific for 'Fuji Suprema'.O objetivo deste trabalho foi identificar porta-enxertos com potencial agronômico competitivo para substituir os tradicionalmente usados no Sul do Brasil para as cultivares-copa de macieira Galaxy e Fuji Suprema cultivadas em solo de replantio. O experimento foi conduzido em Lebon Regis, no Estado de Santa Catarina, nas safras de 2009/2010 a 2014/2015, em delineamento experimental de blocos ao acaso, com quatro repetições. Avaliou-se o desempenho agronômico das copas 'Galaxy' e 'Fuji Suprema', enxertadas sobre G.056, G.202, G.213, G.814, G.896, G.969, M.9 e Marubakaido/M.9. G.896 e G.814 se destacaram pelas produções de frutos anual e acumulada superiores, bem como pela maior regularidade produtiva, embora tenham apresentado menor capacidade ananizante sobre a copa. As maiores massas médias de frutos de 'Galaxy' foram obtidas sobre G.056 e G.213. Para 'Fuji Suprema', G.969 proporcionou frutos menores, enquanto os demais porta-enxertos não diferiram entre si. Todos os porta-enxertos avaliados rebrotaram menos que Marubakaido/M.9 e produziram menos “burrknots” que M.9 e Marubakaido/M.9. No geral, nas condições de solo de replantio, G.202 mostra ser promissor entre os porta-enxertos ananizantes, principalmente para 'Fuji Suprema'. Destacam-se também G.056, G.814 e G.896, sendo os dois primeiros mais específicos para 'Fuji Suprema'

Engineered diets to improve cancer outcomes

Cancer cells acquire a diverse range of metabolic adaptations that support their enhanced rates of growth and proliferation. While these adaptations help tune metabolism to support higher anabolic output and bolster antioxidant defenses, they can also decrease metabolic flexibility and increase dependence on nutrient uptake versus de novo synthesis. Diet is the major source of nutrients that ultimately support tumor growth, yet the potential impact of diet is currently underutilized during the treatment of cancer. Here, we review several forms of dietary augmentation therapy including those that alter the content of food, such as energy or macronutrient restriction, and those that alter the timing of food consumption, like intermittent fasting regimens. We discuss how these dietary strategies can be combined with pharmacologic therapies to exaggerate the metabolic liabilities of different cancer types