7 research outputs found
P07-05. HIV and STI prevalence among men who have sex with men (MSM) recruited through respondent driven sampling (RDS) in Buenos Aires, Argentina
Fil: Pando, MarĂa A. Centro Nacional de Referencia para el SIDA; Argentina.Fil: Marone, RubĂ©n. Nexo AsociaciĂłn Civil; Argentina.Fil: BalĂĄn, IvĂĄn C. Columbia University. HIV Center for Clinical and Behavioral Studies; Estados Unidos.Fil: Dolezal, Curtis. Columbia University. HIV Center for Clinical and Behavioral Studies; Estados Unidos.Fil: Squiquera, Luis. Nexo AsociaciĂłn Civil; Argentina. Fil: Balan, IvĂĄn C. Columbia University. HIV Center for Clinical and Behavioral Studies; Estados Unidos.Fil: Picconi, MarĂa Alejandra. ANLIS Dr.C.G.MalbrĂĄn. Instituto Nacional de Enfermedades Infecciosas. Servicio Virus OncogĂ©nicos; Argentina.Fil: Gonzales, J. ANLIS Dr.C.G.MalbrĂĄn. Instituto Nacional de Enfermedades Infecciosas. Servicio Virus OncogĂ©nicos; Argentina.Fil: Rey, Jorge. Hospital de ClĂnicas JosĂ© de San MartĂn; Argentina.Fil: Fernandez Toscano, M. Hospital de ClĂnicas JosĂ© de San MartĂn; Argentina.Fil: Rodriguez FermepĂn, Marcelo. UBA. Laboratorio de InmunologĂa ClĂnica; Argentina.Fil: Gallo Vaulet, Lucia. UBA. Laboratorio de InmunologĂa ClĂnica; Argentina.Fil: Carballo Dieguez, Alex. Columbia University. HIV Center for Clinical and Behavioral Studies; Estados Unidos.Fil: Avila, MarĂa M. Centro Nacional de Referencia para el SIDA; Argentina.Background
MSM constitute one of the populations most affected by HIV and other STIs in Argentina. Previous prevalence studies were based on convenience samples. RDS, a methodology designed to access hidden populations, is being used for the first time in Argentina to recruit MSM.
Methods
RDS recruitment started in November 2007 with 16 first generation participants (seeds) who were selected for their potential to tap in MSM networks. Recruitment is ongoing. Men must be 18 years of age or older, be residents of Buenos Aires, self-report having sex with men at least 10 times in their lives and at least once in the past six months. They must have a coupon indicating they have been referred by a study participant. Specimens are being collected for HIV and STI diagnosis. All data are weighted using the RDS Analysis Tool (RDSAT).
Results
To date, 333 MSM were recruited through RDS showing a prevalence of 11.3, 16.6, 7.9, 17.6, 4.0 and 88.3% for HIV, HBV, HCV, T. pallidum, Chlamydia and HPV, respectively. Chlamydia and HPV diagnoses were only performed in 73 and 79 participants, respectively. Among HPV positive individuals, 47.8% had almost one of these high risk types (16, 58, 33, 45, 18 and 31) and 32% had multiple infections with 2 or more types.
Conclusion
Compared with previous studies, these results show similar HIV, HBV and T. pallidum prevalences but higher HCV prevalence. For the first time, an elevated prevalence of HPV was detected on MSM, with high frequency of types associated with ano-genital cancer. Preliminary analyses of socio demographic data show that RDS helps recruit a diversity of MSM, particularly of lower socio-economic level usually missed with other recruitment methods. The high prevalence of coinfections in this population should be taken into account if MSM are part of vaccine trials given that STI may increase HIV sexual transmission
P07-05. HIV and STI prevalence among men who have sex with men (MSM) recruited through respondent driven sampling (RDS) in Buenos Aires, Argentina
Fil: Pando, MarĂa A. Centro Nacional de Referencia para el SIDA; Argentina.Fil: Marone, RubĂ©n. Nexo AsociaciĂłn Civil; Argentina.Fil: BalĂĄn, IvĂĄn C. Columbia University. HIV Center for Clinical and Behavioral Studies; Estados Unidos.Fil: Dolezal, Curtis. Columbia University. HIV Center for Clinical and Behavioral Studies; Estados Unidos.Fil: Squiquera, Luis. Nexo AsociaciĂłn Civil; Argentina. Fil: Balan, IvĂĄn C. Columbia University. HIV Center for Clinical and Behavioral Studies; Estados Unidos.Fil: Picconi, MarĂa Alejandra. ANLIS Dr.C.G.MalbrĂĄn. Instituto Nacional de Enfermedades Infecciosas. Servicio Virus OncogĂ©nicos; Argentina.Fil: Gonzales, J. ANLIS Dr.C.G.MalbrĂĄn. Instituto Nacional de Enfermedades Infecciosas. Servicio Virus OncogĂ©nicos; Argentina.Fil: Rey, Jorge. Hospital de ClĂnicas JosĂ© de San MartĂn; Argentina.Fil: Fernandez Toscano, M. Hospital de ClĂnicas JosĂ© de San MartĂn; Argentina.Fil: Rodriguez FermepĂn, Marcelo. UBA. Laboratorio de InmunologĂa ClĂnica; Argentina.Fil: Gallo Vaulet, Lucia. UBA. Laboratorio de InmunologĂa ClĂnica; Argentina.Fil: Carballo Dieguez, Alex. Columbia University. HIV Center for Clinical and Behavioral Studies; Estados Unidos.Fil: Avila, MarĂa M. Centro Nacional de Referencia para el SIDA; Argentina.Background
MSM constitute one of the populations most affected by HIV and other STIs in Argentina. Previous prevalence studies were based on convenience samples. RDS, a methodology designed to access hidden populations, is being used for the first time in Argentina to recruit MSM.
Methods
RDS recruitment started in November 2007 with 16 first generation participants (seeds) who were selected for their potential to tap in MSM networks. Recruitment is ongoing. Men must be 18 years of age or older, be residents of Buenos Aires, self-report having sex with men at least 10 times in their lives and at least once in the past six months. They must have a coupon indicating they have been referred by a study participant. Specimens are being collected for HIV and STI diagnosis. All data are weighted using the RDS Analysis Tool (RDSAT).
Results
To date, 333 MSM were recruited through RDS showing a prevalence of 11.3, 16.6, 7.9, 17.6, 4.0 and 88.3% for HIV, HBV, HCV, T. pallidum, Chlamydia and HPV, respectively. Chlamydia and HPV diagnoses were only performed in 73 and 79 participants, respectively. Among HPV positive individuals, 47.8% had almost one of these high risk types (16, 58, 33, 45, 18 and 31) and 32% had multiple infections with 2 or more types.
Conclusion
Compared with previous studies, these results show similar HIV, HBV and T. pallidum prevalences but higher HCV prevalence. For the first time, an elevated prevalence of HPV was detected on MSM, with high frequency of types associated with ano-genital cancer. Preliminary analyses of socio demographic data show that RDS helps recruit a diversity of MSM, particularly of lower socio-economic level usually missed with other recruitment methods. The high prevalence of coinfections in this population should be taken into account if MSM are part of vaccine trials given that STI may increase HIV sexual transmission
HIV and Other Sexually Transmitted Infections among Men Who Have Sex with Men Recruited by RDS in Buenos Aires, Argentina: High HIV and HPV Infection
The aim of this study was to estimate the prevalence of HIV and other STIs, among MSM from Buenos Aires (2007-2009).Responding Driven Sampling was used for recruitment of MSM. Participants completed a structured web-based survey and provided biological samples.A total of 496 MSM were studied for HIV, HBV, HCV, and T. pallidum infections. Chlamydia and HPV diagnoses were only performed in 98 and 109 participants, respectively. Prevalence of HIV was 17.3%, HBV 22.9%, HCV 7.5%, T. pallidum 20.5%, HPV 83.5%, and C. trachomatis 1.7%. In the year prior to the evaluation, 71% of the participants had had sex with men and/or trans and women (MMW) while 29% had not had sex with women (MM). Comparing MM to MMW, prevalence of HIV (30.7% vs. 11.9%, p<0.001), HBV (36.4% vs. 17.8%, p<0.001), T. pallidum (32.1% vs. 15.7%, p<0.001), and HPV (88.3% vs. 70.4%, pâ=â0.039) were significantly higher among MM, whereas no significant differences were found for HCV and C. trachomatis. The MM group had also significantly higher HIV incidence (5.60 vs. 4.28 per 100 persons-year, pâ=â0.032). HPV genotypes 16, 6, and 11 were the most frequently found; 40.7% of the MSM had more than one genotype and one high risk genotype was detected in 43.6% of participants.Both MM and MMW are at high risk of infection for HIV and other STIs. Rates of HIV, HBV, T. pallidum and HPV infections are higher in the MM group
Number of STIs according to type of partner.
<p>MM: participants whose sexual partners did not include women; MMW: participants whose sexual partners included women. Note: the total column includes men who could not be placed in either group due to missing data.</p
STIs prevalence according to type of partner among 496 MSM recruited through RDS in Buenos Aires, 2007â2009.
<p>MM: participants whose sexual partners did not include women; MMW: participants whose sexual partners included women. Note: the total column includes men who could not be placed in either group due to missing data.</p
Association between HIV and other STIs according to type of partner.
<p>Association between HIV and other STIs according to type of partner.</p