36 research outputs found
Npas4: Linking Neuronal Activity to Memory
Get PDFImmediate-early genes (IEGs) are rapidly activated after sensory and behavioral experience and are believed to be crucial for converting experience into long-term memory. Neuronal PAS domain protein 4 (Npas4), a recently discovered IEG, has several characteristics that make it likely to be a particularly important molecular link between neuronal activity and memory: it is among the most rapidly induced IEGs, is expressed only in neurons, and is selectively induced by neuronal activity. By orchestrating distinct activity-dependent gene programs in different neuronal populations, Npas4 affects synaptic connections in excitatory and inhibitory neurons, neural circuit plasticity, and memory formation. It may also be involved in circuit homeostasis through negative feedback and psychiatric disorders. We summarize these findings and discuss their implications.National Institutes of Health (U.S.) (Grant MH091220-01
Additional file 1: of Identification of novel loci associated with maturity and yield traits in early maturity soybean plant introduction lines
No full textList of 86 lines used in the GWA analyses, along with their corresponding maturity group and fastStructure group. (XLSX 24Â kb
Additional file 7: of Identification of novel loci associated with maturity and yield traits in early maturity soybean plant introduction lines
No full textGenome-wide association analysis Manhattan plots for soybean agronomic traits of interest using various genotyping methods. (PPTX 941Â kb
Additional file 2: of Identification of novel loci associated with maturity and yield traits in early maturity soybean plant introduction lines
No full textAverage trait values across the five site-years. (PPTX 87Â kb
Additional file 5: of Identification of novel loci associated with maturity and yield traits in early maturity soybean plant introduction lines
No full textLocation of gaps and their distances in the merged data set. (XLSX 12Â kb
Additional file 6: of Identification of novel loci associated with maturity and yield traits in early maturity soybean plant introduction lines
No full textQuantile-quantile (QQ) plots of different genome-wide association study analytical approaches for various soybean agronomic traits. (PPTX 648Â kb
Additional file 3: of Identification of novel loci associated with maturity and yield traits in early maturity soybean plant introduction lines
No full textQuantile-quantile (QQ) plots of phenotypic traits demonstrating normal distributions. (PPTX 131Â kb
Detailed rankings of 11 candidate reference genes from qRT-PCR data, given by RefFinder in <i>G</i>. <i>pallida</i>.
No full text<p>Detailed rankings of 11 candidate reference genes from qRT-PCR data, given by RefFinder in <i>G</i>. <i>pallida</i>.</p
Description of genes and primers used in this study.
No full text<p>Description of genes and primers used in this study.</p
