Phylogenetic tree based on the core-genome multi-locus sequence typing (cgMLST) analysis of the 80 whole-genome sequenced <i>S</i>. Infantis strains studied, isolated from food (red squares; n = 27), farm and industry environments (green squares; n = 24), humans (blue squares; n = 19), animals (yellow squares; n = 7) and animal feed (orange squares; n = 3) between 2013 and 2018 in Brazil.

S. Infantis reference strain SINFA LN649235.1 (black square) was included for comparison purposes. Additional information regarding the isolation sources, efflux pump encoding genes (EPEG) and heavy metal tolerance genes are included. Profile 1 (acrA, acrB, baeR, crp, emrB, emrR, golS, hns, kdpE, kpnF, marA, marR, mdfA, mdtK, msbA, rsmA, sdiA, soxR, soxS); Profile 2 (acrA, acrB, baeR, crp, emrB, emrR, golS, hns, kdpE, kpnF, marA, marR, mdtK, msbA, rsmA, sdiA, soxR, soxS, tet(A)); Profile 3 (acrA, acrB, baeR, crp, emrB, emrR, golS, hns, kdpE, kpnF, marA, marR, mdtK, msbA, rsmA, sdiA, soxR, soxS); Profile 4 (acrA, acrB, baeR, crp, emrB, emrR, hns, kdpE, kpnF, marA, marR, mdfA, mdtK, msbA, rsmA, sdiA, soxR, soxS).</p

Antimicrobial resistance and plasmid profiles of the 80 <i>Salmonella</i> Infantis strains studied isolated from food (n = 27), the environment (n = 24), humans (n = 19), animals (n = 7) and animal ration (n = 3) between 2013 and 2018 in Brazil.

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Antimicrobial efflux pump encoding gene (ARG) profiles detected among the 80 <i>Salmonella</i> Infantis strains studied isolated from food (n = 27), farm and industry environments (n = 24), humans (n = 19), animals (n = 7) and animal feed (n = 3) in Brazil between 2013 and 2018.

Antimicrobial efflux pump encoding gene (ARG) profiles detected among the 80 Salmonella Infantis strains studied isolated from food (n = 27), farm and industry environments (n = 24), humans (n = 19), animals (n = 7) and animal feed (n = 3) in Brazil between 2013 and 2018.</p

List of the drug classes and resistance mechanisms as referred by the Comprehensive Antibiotic Resistance Database (CARD) of the efflux pump encoding genes detected among the 80 sequenced <i>Salmonella</i> Infantis strains studied isolated from food (n = 27), farm and industry environments (n = 24), humans (n = 19), animals (n = 7) and animal feed (n = 3) in Brazil between 2013 and 2018.

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Phylogenetic tree based on the core-genome multi-locus sequence typing (cgMLST) analysis of the 120 genomes of <i>S</i>. Infantis strains from Brazil, Canada, Ecuador Germany, Mexico, Peru, South Africa, United Kingdom (UK) and United States (US).

The 120 strains were isolated from food (red squares), environments (green squares), humans (blue squares), animals (yellow squares) and animal feed (orange squares). S. Infantis reference strain SINFA LN649235.1 (black square) was included for comparison purposes. Additional information regarding the isolation sources, core-genome sequence types (cgSTs) and the number and percentages of the identified alleles are included.</p

Strain identifiers and isolation data of the 80 <i>Salmonella</i> Infantis strains studied isolated from food (n = 27), farm and industry environments (n = 24), humans (n = 19), animals (n = 7) and animal feed (n = 3) between 2013 and 2018 in Brazil.

Strain identifiers and isolation data of the 80 Salmonella Infantis strains studied isolated from food (n = 27), farm and industry environments (n = 24), humans (n = 19), animals (n = 7) and animal feed (n = 3) between 2013 and 2018 in Brazil.</p

Metadata of the additional 40 <i>Salmonella</i> Infantis genomes from diverse countries recovered from NCBI’s Pathogen Detection platform and included in the core genome multi-locus sequence typing (cgMLST) analysis.

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Statistical analysis based on the Chi-Square test to verify the association among the 46 S. Infantis strains co-harboring <i>golS</i>, <i>golT</i>, <i>arsR</i> and the profile 1 of efflux pump encoding genes and 29 strains harboring <i>golS</i>, <i>golT</i>, <i>arsR</i>, the <i>sil</i> operon and the profile 2 of efflux pump encoding genes.

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