A. Large flat lesion on the arm of a 32 years old man. B. at the time of surgical excision, dermoscopy reveals the presence of asymmetry of color and structure, with pigment network and regressive features suggestive for melanoma. C and D. Digital dermoscopic follow up of the lesion reveals the asymmetric growth of the tumor (circle) over time.

<p>A. Large flat lesion on the arm of a 32 years old man. B. at the time of surgical excision, dermoscopy reveals the presence of asymmetry of color and structure, with pigment network and regressive features suggestive for melanoma. C and D. Digital dermoscopic follow up of the lesion reveals the asymmetric growth of the tumor (circle) over time.</p

A. On histology, there is a diffuse, lentiginous proliferation made up by pigmented, monomorphous melanocytes. B and C. The cells are cytologically bland and mainly located in the lower epidermis.

<p>Pagetoid spread is not a feature.</p

List of cases missing a clinical-pathologic correlation: demographic description and reasons for diagnosis re-appraisal.

<p>List of cases missing a clinical-pathologic correlation: demographic description and reasons for diagnosis re-appraisal.</p

A. Solitary hyperpigmented flat lesion on the shoulder of a 52 years old lady. B. dermoscopy reveals an irregularly shaped lesion with atypical network.

<p>A. Solitary hyperpigmented flat lesion on the shoulder of a 52 years old lady. B. dermoscopy reveals an irregularly shaped lesion with atypical network.</p

A. Histopathology shows an irregular melanocytic lesion, associated with a slightly thickened epidermis. B and C. Junctional melanocytes are rather pleomorphic while the dermal component is bland and monomorphous.

<p>Fibrosis and inflammation are evident in the superficial dermis.</p