Up- and down-modulated inflammatory and chemokine genes in AIRmax and AIRmin mice.

<p>Mouse Gene 1.0(SAM) software (Two class unpaired, FDR ≤5%) that examined the data from four biological replicates on each line.</p

Differentially-expressed major candidate genes detected in microarray related to PIA QTL.

<p>Differentially expressed genes in AIRmax and AIRmin mice. Mouse Gene 1.0 ST Array was used. Differentially expressed genes were detected using Significance of Analysis of Microarray (SAM) software (Two class unpaired, FDR ≤5%) that examined the data from four biological replicates on each line.</p

Mapping of the QTL regulating PIA severity phenotype in mice selected for acute inflammation.

<p>SNPs were genotyped in F2 intercrosses employing the Bead-Array Platform (Illumina Inc. San Diego, CA) and using the 1449-SNP loci mouse linkage panel as described. Searches for QTL affecting the arthritis severity phenotype under study were carried out using genome-wide linkage analysis between genotypes and phenotypes by interval mapping, using GridQTL version 3.1.0.</p

Differentially expressed genes on chromosome 5 between AIRmax and AIRmin mice.

<p>Mouse Gene 1.0(SAM) software (Two class unpaired, FDR ≤5%) that examined the data from four biological replicates on each line.</p

qPCR versus Microarray results correlations and primers used.

<p>Relative differences were calculated according to the delta-delta Ct method. Microarray data was correlated with qPCR results using Pearson’s analyses and the same four samples on each line.</p

Differentially expressed genes on chromosome 8 in AIRmax and AIRmin mice.

<p>Mouse Gene 1.0(SAM) software (Two class unpaired, FDR ≤5%) that examined the data from four biological replicates on each line.</p