3 research outputs found
Antibacterial activity of phenylpropanoids derived from cinnamic acid
In this work, we present antibacterial activity of a 22 phenylpropanoids derived from cinnamic
acid, recently reported as antifungal agents by our group. Some of these compounds are commercial,
others are natural products and some of them were obtained by synthesis. Antibacterial activity was
determined in two stages. At first, a screening was made by an easy, economic and fast assay using a commercial
lyophilized of Gram (+) bacteria. Compounds that showed activity at the screening were tested
against Gram (+) and Gram (-) pathogens.Colegio de Farmacéuticos de la Provincia de Buenos Aire
Acute toxicity study of commercial antifungal drugs using Poecilia reticulata
Commercial antifungal drugs possess important side effect; being toxicity the main limitation
of such compounds. We report here a study of acute toxicity of four well-known commercial antifungal
drugs; two of them used in human medicine (griseofulvine and miconazole) and the other two used against
phytopatogens fungi (carbendazin and benomil). Toxic effects of these compounds were evaluated using an
acute toxicity test on fish of the specie Poecilia reticulata.Colegio de Farmacéuticos de la Provincia de Buenos Aire