Schematic representation of the molecular structure of the six gilthead sea bream mucins.

<p>Various functional domains are indicated in boxes: <i>O</i>-glycosylated region or PTS domain (yellow), extracellular proteolytic cleavage site SEA domain (orange), transmembrane domain (TM) (red), immunoglobulin domain (Ig) (grey), vW-D domain (dark blue), C8 domain (blue), and cystine knot domain (CK) (light blue). Discontinuous lines at NH₂ or COOH ends represent the predicted size of the lacking sequences in partial proteins according to homology comparisons.</p

Relative mRNA expression levels of mucins in the posterior intestine of gilthead sea bream fed vegetable oils (VO) or fish oil (FO) diets and infected by <i>Enteromyxum leei</i> (RCPT) or kept unexposed to the parasite (CTRL) (Trial 2).

<p>Each bar represents the mean ± the SEM of 6–10 animals. Asterisk indicate statistically significant differences (P<0.05) between CTRL fish fed different diets. Significant differences were also found between each CTRL group and its corresponding RCPT group for the four mucins (not indicated to avoid confusion in symbol interpretations).</p

Relative mRNA expression of gilthead sea bream mucins in different tissues.

<p>For each tissue, the most abundant mucin is in bold face and different superscript letters stand for statistically significant differences (P<0.05) between mucins.</p

Phylogenetic tree of membrane-bound and secreted gel-forming mucins.

<p>Gilthead sea bream mucins are highlighted in yellow. GenBank accession numbers are provided for each sequence.</p

Forward and reverse primers for real-time PCR.

<p>Forward and reverse primers for real-time PCR.</p

Data Mining Framework For Discovering and Clustering Phenotypes of Atypical Diabetes

Supplemental tables and figures for "Data Mining Framework For Discovering and Clustering Phenotypes of Atypical Diabetes"</p