Phylogenetic tree of the HIV-1 subtype B dataset.

<p>The potential transmission cluster (n = 143) is highlighted in red, other subtype B sequences are colored in black and the reference sequences from other subtypes/CRFs are colored in grey.</p

Maximum likelihood tree of the CV-cluster.

<p>It includes sequences from the city of Valencia (red), from other Spanish cities (blue) and sequences from other countries retrieved by BLAST analysis (grey). aLRT support values defining the CV-cluster (n = 113) and the larger Spanish clade it derives from (n = 194) are shown.</p

Akaike's Information Criterion (AICM) values and tMRCA of the CV cluster for three demographic models.

<p>Akaike's Information Criterion (AICM) values and tMRCA of the CV cluster for three demographic models.</p

Sampling distribution of HIV-1 subtype B sequences.

<p>Sequences from patients inhabiting the city of Valencia or its metropolitan area are represented in blue (n = 1134) and those belonging to the transmission cluster sampled in this city are shown in red (n = 105).</p

Epidemiological characteristics of the patients.

<p>Epidemiological characteristics of the patients.</p

Dated phylogeny of the 143 sequences from the initial CV cluster.

<p>Branch lengths represent years. The CV cluster is highlighted in black. Dots on nodes represent posterior probabilities ≥ 0.90.</p

Comparison of adherence and virological failure between arms.

<p>Comparison of adherence and virological failure between arms.</p

CONSORT flow diagram showing disposition of patients throughout the study from baseline to week 24.

<p>CONSORT flow diagram showing disposition of patients throughout the study from baseline to week 24.</p

Overview of adverse events (AEs).

<p>Overview of adverse events (AEs).</p

Baseline characteristics of the study patients.

<p>Baseline characteristics of the study patients.</p