A. Global distribution of sequenced <i>H</i>. <i>pylori</i> strains from different populations B. phylogenetic comparison based on seven house-keeping genes (Left) and core genomes (Right).

<p>A. Global distribution of sequenced <i>H</i>. <i>pylori</i> strains from different populations B. phylogenetic comparison based on seven house-keeping genes (Left) and core genomes (Right).</p

Gene contents of the predicted phage YN4–84P.

<p>Gene contents of the predicted phage YN4–84P.</p

Neighbor-joining tree based on the sequence diversity of <i>cagA</i> (Left) and <i>cagPAI</i> (Right).

<p>YN4–84 is highlighted in red.</p

a. Subsystem distribution statistics of <i>Helicobacter pylori</i> strain YN4–84 generated by the rapid annotation using a subsystem technology server. b. Subsystem distribution statistics of <i>Helicobacter pylori</i> strain YN1–91 generated by the rapid annotation using a subsystem technology server.

<p>a. Subsystem distribution statistics of <i>Helicobacter pylori</i> strain YN4–84 generated by the rapid annotation using a subsystem technology server. b. Subsystem distribution statistics of <i>Helicobacter pylori</i> strain YN1–91 generated by the rapid annotation using a subsystem technology server.</p

Gene content of YN4–84P.

<p>Gene content of YN4–84P.</p

Genomic features and backgrounds of the 47 <i>H</i>. <i>pylori</i> strains used in this study

<p>Genomic features and backgrounds of the 47 <i>H</i>. <i>pylori</i> strains used in this study</p

Global overview of genomic diversity of YN4–84 and YN1–91 with other 46 <i>H</i>. <i>pylori</i> genome sequences.

<p>The four regions with most divergence were labeled with brown arcs along the chromosome.</p

Global alignment of YN4–84 and YN1–91.

<p>The black arrows above YN4–84 show the insertion of YN4–84P and its flanking gene fragments.</p

Map of 18 CPS loci.

<p>The same color module in different strains means that the sequences in this region are similar. Blank regions indicate a unique region in a sequence. The name of the sequences is made up of the strain ID and serotype. The comparison was made using Mauve 2.4.0 software.</p

Comparison of sequences of CPS loci of <i>C</i>. <i>jejuni</i> strains.

<p>(A) Comparison of the sequences of the CPS loci of <i>C</i>. <i>jejuni</i> HS9 (strain BJ-CJD63), HS37 (strain HB-CJGB-LL) and HS31 (strain BJ-CJD39); (B) comparison of the CPS loci of <i>C</i>. <i>jejuni</i> HS12 (strain BJ-CJD70) and a strain of HS42 (strain ATCC 43461); (C) comparison of the CPS loci of <i>C</i>. <i>jejuni</i> HS21 (strain JL-CJHLIU1-1), the HS15 type strain (strain ATCC 43442), and an HS8/17 strain (strain 43444). Red bars represent identical regions between loci.</p