7 research outputs found

    Microstructure and mechanical properties of Mg-2Sn-1.95Ca-0.5Ce alloy with different extrusion speeds

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    Effects of extrusion speeds (0.3, 1.2, 1.8 and 3.5 mm s ^−1 ) on the microstructure and mechanical properties of the Mg–2Sn–1.95Ca–0.5Ce (TXCe220) alloy were analyzed by various detection methods in this article. The results have revealed that extrusion speed exerts a prominent influence towards grain size, recrystallization fraction and texture. As the extrusion speed increases, the microstructure characteristics transform from bimodal grain morphology to the near complete dynamical recrystallization (DRX). The tensile yield strength of TXCe220 decreased from 365 MPa to 180 MPa accompanied by the elongation increasing from 4.0 % to 19.4 % when the ram speed rises from 0.3 mm s ^−1 to 3.5 mm/s. The high yield strength of low-speed extruded alloys should be mainly ascribed to the nano-scale Mg _2 Ca with diameter of 30–80 nm precipitates, fine DRX grains and strong texture

    Microstructure and mechanical properties of Mg-2Zn-0.3Ca-0.5La magnesium alloy extruded with different temperatures

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    The extrusion tests of the Mg-2Zn-0.3Ca-0.5La (ZXLa200) alloy were carried out at different extrusion temperatures (260 °C–320 °C), and the mechanical properties and microstructure were studied and analyzed by means of optical microscope, scanning electron microscope, x-ray diffraction, transmission electron microscope, and tensile testing. The research have demonstrated significant influence of Extrusion temperature towards grain size, recrystallization grains and texture. With the extrusion temperature increases, the recrystallization grain of the extruded ZXLa200 alloy increases, but the texture intensity decreases. During the extrusion process, a large amount of Ca _2 Mg _6 Zn _3 (50–200 nm) precipitates are precipitated, which inhibited the growth of dynamic recrystallization grains and improved the yield strength of the alloys. The tensile yield strength and elongation of extruded ZXLa200 alloy were acquired to be 375 MPa, 5.9% at 260 °C and 310 MPa, 19.2% at 320 °C

    Establishment of a New Equation for Ultrasonographic Estimated Foetal Weight in Chongqing: A Prospective Study

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    Background: Variations in foetal growth between populations should not be ignored, and a single universal standard is not appropriate for everyone. Therefore, it is necessary to develop a new ultrasound estimation equation that adapts better to regional population characteristics. The purpose of this study was to create a new equation for ultrasound estimation of foetal weight according to the local population in Chongqing and compare it with representative equations. Methods: This prospective study included data on pregnant women who gave birth to a child at full term in our hospital from December 2016 to November 2019. Foetal ultrasound parameters included biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), and femur diaphysis length (FDL). The foetal weight compensation model was established by using the second-order linear regression model, and then, the foetal weight equation was established by utilizing the multiple reverse elimination regression technique. Last, the absolute error and relative error were used to compare the accuracy of the equations established in this study with representative equations. Results: Through the foetal weight compensation equation, the new equation suitable for Chongqing foetuses was successfully established with the variables of BPD, HC, AC, and FDL. The following foetal weight prediction equation was established in this study: Log10(EFW) = 3.002741 + 0.00005944 × (BPD2) + 0.00000222 × (HC2) – 0.000002078 × (AC2) + 0.00004262 × (FDL2) – 0.008753 × BPD – 0.000884 × HC + 0.003206 × AC – 0.002894 × FDL (BPD: mm; HC: mm; AC: mm; FDL: mm). In the sets established by the 1925 data, the mean absolute error and standard deviation of the estimation error of the new equation were 178.9 g and 140.3 g respectively. In the validation sets established with 300 data points, the mean absolute error and standard deviation of the new equation were 173.08 g and 128.59 g respectively. Compared with representative equations, the mean absolute error and the standard deviation of the new equation were the lowest. The equation established in this study better predicted foetal weight (p < 0.001). Conclusions: According to the local population characteristics of Chongqing, this study created a foetal weight estimation equation that is more accurate and suitable. This equation is clinically valuable for the monitoring and management of foetal weight

    Poly(α-l-lysine)-based nanomaterials for versatile biomedical applications: Current advances and perspectives

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    Poly(α-l-lysine) (PLL) is a class of water-soluble, cationic biopolymer composed of α-l-lysine structural units. The previous decade witnessed tremendous progress in the synthesis and biomedical applications of PLL and its composites. PLL-based polymers and copolymers, till date, have been extensively explored in the contexts such as antibacterial agents, gene/drug/protein delivery systems, bio-sensing, bio-imaging, and tissue engineering. This review aims to summarize the recent advances in PLL-based nanomaterials in these biomedical fields over the last decade. The review first describes the synthesis of PLL and its derivatives, followed by the main text of their recent biomedical applications and translational studies. Finally, the challenges and perspectives of PLL-based nanomaterials in biomedical fields are addressed
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