The adsorption and release characteristics of CPFX in porous starch produced through different drying methods

The drug adsorption and release characteristics of porous starches produced through hot air drying, spray drying, and vacuum freeze drying were investigated using ciprofloxacin as model drug. A UV/visible spectrophotometer, Fourier-transform infrared spectrometer, differential scanning calorimeter, and X-ray diffractometer were used to determine the drug adsorption/release, drug/starch interaction, glass transition, and crystallinity of porous starch samples. The amount of ciprofloxacin adsorbed in three different porous starches was 5.58%, 8.91%, and 11.43%, respectively. The ciprofloxacin-loaded porous starches had glass-transition-related endothermic peaks between 55°C and 65°C and melting-related endothermic peaks between 120°C and 150°C. Up to 75% of the loaded ciprofloxacin was released from the freeze-dried sample within 30 hrs. The freeze-dried porous starch also showed higher ciprofloxacin loading rate, higher glass transition temperature, and higher ciprofloxacin release rate. A two-phase dynamic drug release model was found to satisfactorily fit the release kinetics of ciprofloxacin (R2 > 0.995). © 2013 Copyright Taylor and Francis Group, LLC.C

Effect of flaxseed meal on the dynamic mechanical properties of starch-based films

Starch (S)-flaxseed meal (FM) biofilms were prepared from potato and maize starch by incorporating FM up to 15% (dry solid basis) and using glycerol as plasticizer. The dynamic mechanical properties, tensile properties and water vapor permeability (WVP) of these films were measured. The storage modulus of both the starch (control) and starch-FM films decreased as temperature increased. Ta

Effect of high-pressure homogenization on the structure of cassava starch

Cassava starch suspension was homogenized at different pressures (0, 20, 40, 60, 80, and 100 MPa) with a high-pressure homogenizer. To investigate the effect of high-pressure homogenization on the structure of cassava starch, the samples were characterized using microscopy, laser scattering, and X-ray diffraction techniques, with native and heat gelatinized cassava starches as controlled samples. The temperature of starch suspension increased linearly with applied pressure at a rate of 0.187 degrees C/MPa. Microscopy studies showed that cassava starch was partly gelatinized after high-pressure homogenization, and the degree of gelatinization increased with homogenizing pressure. Results of laser scattering measurements suggested a considerable increase in particle size after homogenization at 100 MPa as a result of granule swelling. The Xray diffraction pattern showed that there was no evident change after homogenization suggesting that the crystalline structure of starch granules was resistant to high-pressure homogenization

Effects of Defatted Flaxseed Addition on Rheological Properties of Wheat Flour Slurry

Rheological property of defatted flaxseed-added wheat flour dispersions was investigated as a function of defatted flaxseed concentration (0-20%), NaCl concentration (0, 0.6, and 1.2%), sucrose concentration (0, 5, and 10%), and slurry concentration (33and 62.5%). Frequency sweep tests at 20 degrees C and temperature sweep tests from 20 to 90 degrees C were applied to the samples. The experimental measurements demonstrated that the viscoelastic moduli of samples increased with the increase in defatted flaxseed concentration from 0 to 20% and decreased with the increase in NaCl, sucrose, and water concentration at 20 degrees C. The gelatinization temperatures of the defatted flaxseed-wheat slurry samples were delayed with the addition of defatted flaxseed, NaCl, and sucrose but hastened with the addition of water

Effect of moisture content and heating rates on the thermal properties of rice embryos measured by differential scanning calorimetry

The effect of moisture content on the thermal properties of rice embryos was investigated using differential scanning calorimetry (DSC). A long grain hybrid rice variety (Jinyou 974) grown in Hunan Province of China was selected in this investigation. The temperature scanning tests were carried out from 20°C to 180°C at different heating rates from 2°C/min to 20°C/min. Consistently higher values of glass transition temperature (Tg) were measured when higher heating rates were used during DSC measurements at every set of moisture contents. The Tg values decreased from (65.28±0.38)°C to (31.08±0.26)°C with increase in moisture content from (10.7±0.3)% to (22.0±0.7)% (w/w). The analysis of variance and the regression analysis showed that both the linear function and Gordon Taylor model can adequately represent the variation of Tg with moisture content (R2 > 0.96)