271 research outputs found

    Chemical vapour deposition and atomic layer deposition of amorphous and nanocrystalline metallic coatings: towards deposition of multimetallic films

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    This paper provides a prospective insight on chemical vapour deposition (CVD) and atomic layer deposition (ALD) as dry techniques for the processing of amorphous and nanocrystalline metallic thin films. These techniques are part of major technologies in application fields such as microelectronics, energy, or protective coatings. From thermodynamic analysis, areas of investigation to generate a set of materials with the strongest propensity for amorphization as well as useful guidelines for the target phase material deposition are provided. Prospective to develop MOCVD (metalorganic chemical vapour deposition) and ALD of intermetallic films, in view of fabrication of metallic glass thin films is proposed. Examples from selected ALD and MOCVD single element metallic deposition processes will be described to illustrate the effect of deposition parameters on the physico-chemical properties of the films. This processing approach is particularly promising for metallic glass thin films

    Les « morts vivants »  Ă  Cam Ne. Le premier « Zippo raid »  de la guerre du ViĂȘt-nam

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    Le 3 aoĂ»t 1965, la compagnie D du 1st Battalion, 9thMarines, investit le village de Cam Ne, au Sud ViĂȘt-nam. L'opĂ©ration « search and destroy » est filmĂ©e par un correspondant de CBS News, Morley Safer. Les images de la destruction d’un village sud-viĂȘtnamien par les Marines choquent profondĂ©ment les États-Unis tout en donnant naissance au terme de « zippo raid ». Pourtant, l’incendie de ces maisons s’inscrit dans l’évolution du conflit viĂȘtnamien lui-mĂȘme avec l’intervention de plus en plus massive des AmĂ©ricains au Sud ViĂȘt-nam.On August 3, 1965, Company D of the 1st Battalion, 9th Marines, surrounded the village of Cam Ne in South Vietnam. The “search and destroy” operation was filmed by CBS News correspondent Morley Safer. The images of the destruction of a South Vietnamese village by Marines deeply shocked the United States while giving rise to the term “zippo raid”. However, the burning of these houses was part of the evolution of the Vietnamese conflict itself with the more and more massive intervention of Americans in South Vietnam

    Les « morts vivants »  Ă  Cam Ne. Le premier « Zippo raid »  de la guerre du ViĂȘt-nam

    Get PDF
    Le 3 aoĂ»t 1965, la compagnie D du 1st Battalion, 9thMarines, investit le village de Cam Ne, au Sud ViĂȘt-nam. L'opĂ©ration « search and destroy » est filmĂ©e par un correspondant de CBS News, Morley Safer. Les images de la destruction d’un village sud-viĂȘtnamien par les Marines choquent profondĂ©ment les États-Unis tout en donnant naissance au terme de « zippo raid ». Pourtant, l’incendie de ces maisons s’inscrit dans l’évolution du conflit viĂȘtnamien lui-mĂȘme avec l’intervention de plus en plus massive des AmĂ©ricains au Sud ViĂȘt-nam.On August 3, 1965, Company D of the 1st Battalion, 9th Marines, surrounded the village of Cam Ne in South Vietnam. The “search and destroy” operation was filmed by CBS News correspondent Morley Safer. The images of the destruction of a South Vietnamese village by Marines deeply shocked the United States while giving rise to the term “zippo raid”. However, the burning of these houses was part of the evolution of the Vietnamese conflict itself with the more and more massive intervention of Americans in South Vietnam

    Rab27a: A key to melanosome transport in human melanocytes

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    Normal pigmentation depends on the uniform distribution of melanin-containing vesicles, the melanosomes, in the epidermis. Griscelli syndrome (GS) is a rare autosomal recessive disease, characterized by an immune deficiency and a partial albinism that has been ascribed to an abnormal melanosome distribution. GS maps to 15q21 and was first associated with mutations in the myosin-V gene. However, it was demonstrated recently that GS can also be caused by a mutation in the Rab27a gene. These observations prompted us to investigate the role of Rab27a in melanosome transport. Using immunofluorescence and immunoelectron microscopy studies, we show that in normal melanocytes Rab27a colocalizes with melanosomes. In melanocytes isolated from a patient with GS, we show an abnormal melanosome distribution and a lack of Rab27a expression. Finally, reexpression of Rab27a in GS melanocytes restored melanosome transport to dendrite tips, leading to a phenotypic reversion of the diseased cells. These results identify Rab27a as a key component of vesicle transport machinery in melanocytes

    An overview of knowledge sharing in new product development

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    This paper provides an overview of some of the issues in knowledge management related to the sharing of knowledge in new product development. Previous research and concepts reported by international researchers, and examples of the research projects carried out by the authors will be introduced. The paper first provides an overview of the history and importance of innovation and challenges in manufacturing. Then the importance of new product development in the sustainable success of manufacturing enterprises in the globalised business operations is discussed. The formalisation and modelling of product development processes will also be introduced. The concept and different definitions of knowledge management by previous researchers are then introduced, with further discussion on knowledge sharing. At this point, the authors’ research in knowledge sharing is also introduced. Finally, the trend of using social media and Enterprise 2 technologies in knowledge management and sharing is introduced using the recent research projects of the authors as examples

    Use of anticoagulants and antiplatelet agents in stable outpatients with coronary artery disease and atrial fibrillation. International CLARIFY registry

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