Plan de negocios Webmanlogistics

99 Páginas.Plataforma tecnológica que combina los conceptos de tucarro.com, e-bay, elempleo.com, Amazon y un sistema de administración de transportes, para que a través del Internet y los servicios de telefonía celular, los diferentes actores en la cadena de valor del transporte (Generadores de carga, empresas transportadoras, transportistas, entidades regulatorias del sector, empresas proveedoras de insumos para el sector, empresas proveedoras de servicios de mantenimiento, hospedaje, seguimiento satelital o de apoyo en ruta y servicios financieros) puedan hacer intercambios comerciales fáciles y seguros de todo índole, que les generen valores agregados. Para el desarrollo de dicha plataforma requerimos definir qué tipo de servicios se le ofrecerá a cada actor y establecer quiénes son los principales competidores

Spectral features of resting-state EEG in Parkinson's Disease: A multicenter study using functional data analysis

Objective This study aims 1) To analyse differences in resting-state electroencephalogram (rs-EEG) spectral features of Parkinson's Disease (PD) and healthy subjects (non-PD) using Functional Data Analysis (FDA) and 2) To explore, in four independent cohorts, the external validity and reproducibility of the findings using both epoch-to-epoch FDA and averaged-epochs approach. Methods We included 169 subjects (85 non-PD; 84 PD) from four centres. Rs-EEG signals were preprocessed with a combination of automated pipelines. Sensor-level relative power spectral density (PSD), dominant frequency (DF), and DF variability (DFV) features were extracted. Differences in each feature were compared between PD and non-PD on averaged epochs and using FDA to model the epoch-to-epoch change of each feature. Results For averaged epochs, significantly higher theta relative PSD in PD was found across all datasets. Also, higher pre-alpha relative PSD was observed in three of four datasets in PD patients. For FDA, similar findings were achieved in theta, but all datasets showed consistently significant posterior pre-alpha differences across multiple epochs. Conclusions Increased generalised theta, with posterior pre-alpha relative PSD, was the most reproducible finding in PD.publishedVersio