ROC analysis for total and free thiol angiotensinogen.

<p>ROC analysis for total and free thiol angiotensinogen.</p

Free thiol angiotensinogen levels in patients with pre-eclampsia and healthy pregnant control individuals.

<p>Levels of free thiol angiotensinogen are expressed as a percentage of the in-house standard (**** p<0.0001).</p

Demographic characteristics of the patient and control groups.

<p>BMI = body mass index, Parity status = number of pregnancies including the current pregnancy</p><p>Demographic characteristics of the patient and control groups.</p

Clinical and laboratory characteristics of the patient and control groups.

<p>BP = Mean blood pressure on at least 2 occasions ≥ 4 h apart, but not >7 days apart; LDH = lactate dehydrogenase; SGOT = Serum glutamic oxaloacetic transaminase; SGPT <i>=</i> serum glutamic-pyruvic transaminase; BUN = blood urea nitrogen</p><p>Clinical and laboratory characteristics of the patient and control groups.</p

Total plasma angiotensinogen levels (μg/ml) in patients with pre-eclampsia and healthy pregnant control individuals.

<p>The amount of total plasma angiotensinogen was derived from a standard curve constructed from known concentrations of purified angiotensinogen. NS = Not Significant.</p

Total angiotensinogen plasma level is the sum of the plasma levels of the oxidized and reduced forms of angiotensinogen.

<p>Total angiotensinogen plasma level is the sum of the plasma levels of the oxidized and reduced forms of angiotensinogen.</p

ROC curve for total angiotensinogen.

<p>ROC curve for total angiotensinogen.</p

ELISA method for measuring free thiol angiotensinogen plasma levels.

<p>Biotin-MPB is added to plasma which labels free thiol (SH) angiotensinogen (ATG). The unincorporated Biotin-MPB is removed by acetone precipitation. Biotin-MPB labelled free thiols of ATG are specifically bound by streptavidin coated plates and bound free thiol ATG is quantified with a specific monoclonal antibody to ATG.</p

ROC curve for free thiol angiotensinogen.

<p>ROC curve for free thiol angiotensinogen.</p