5 research outputs found
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A solitary lesion of idiopathic calcinosis cutis in an infant: subepidermal nodular calcinosis or milia-like idiopathic calcinosis cutis?
Milia-like idiopathic calcinosis cutis (MICC) and subepidermal calcified nodule (SCN) are described as different entities under the heading of idiopathic calcinosis cutis. Although there are some clinical differences, they share many features. Whereas MICC lesions are located mostly on the extremities and rarely on the face, SCN manifests itself mostly on the face, rarely on the extremities. Milia-like idiopathic calcinosis cutis almost always presents with multiple lesions, whereas SCN shows mainly solitary and rarely multiple lesions. Association with Down syndrome (DS) has been reported in up to two-third of the cases with MICC, but not in SCN. We herein present a 5-months-old girl without DS, manifesting a 2mm solitary, white hard papule surrounded by erythema, located on the finger. Histopathologic findings revealed the presence of dermal calcium deposits. When a solitary papular lesion of idiopathic calcinosis is seen in a child, especially if not associated with DS, it is difficult to differentiate MICC from SCN. We believe that these entities may represent variants of the same pathology and it may be more appropriate to designate a solitary lesion as SCN, regardless of its location
Recommended from our members
A solitary lesion of idiopathic calcinosis cutis in an infant: subepidermal nodular calcinosis or milia-like idiopathic calcinosis cutis?
Milia-like idiopathic calcinosis cutis (MICC) and subepidermal calcified nodule (SCN) are described as different entities under the heading of idiopathic calcinosis cutis. Although there are some clinical differences, they share many features. Whereas MICC lesions are located mostly on the extremities and rarely on the face, SCN manifests itself mostly on the face, rarely on the extremities. Milia-like idiopathic calcinosis cutis almost always presents with multiple lesions, whereas SCN shows mainly solitary and rarely multiple lesions. Association with Down syndrome (DS) has been reported in up to two-third of the cases with MICC, but not in SCN. We herein present a 5-months-old girl without DS, manifesting a 2mm solitary, white hard papule surrounded by erythema, located on the finger. Histopathologic findings revealed the presence of dermal calcium deposits. When a solitary papular lesion of idiopathic calcinosis is seen in a child, especially if not associated with DS, it is difficult to differentiate MICC from SCN. We believe that these entities may represent variants of the same pathology and it may be more appropriate to designate a solitary lesion as SCN, regardless of its location
Comment On Dermoscopic Features of Seborrheic Keratoses Following Cryotherapy
Seborrheic keratosis (SK) is the most common benign tumor in older individuals.
Freezing with liquid nitrogen has been widely used as a method of
treatment. In one of our patients treated with cryotherapy, follow-up dermoscopical
image of the lesion raised a concern for regressing malignant
lesion in the post treatment period. Information on the dermoscopy of SK
treated with cryotherapy was not available. Consequently, we gathered and
retrospectively analysed the pictures taken during healing periods of four
SK without choosing a specific type. Besides dermoscopic structures specific
for SK, coarse and fine gray granules arranged in a linear or annular pattern
were also noted. These features have been reported in various malignant
tumors before. Most of the time, clinical diagnosis of SK is not an issue;
although rarely though rare malignant transformation of SK has been reported.
Furthermore, SK may be found with another malignant condition
as a collision tumor. Consequently, we think all the dermoscopic features
presented are compatible with cryotherapy induced lichenoid keratosis like
lesions. As a conclusion, it is important to know and document the dermoscopic
findings that occur in the post-cryotherapy healing period to prevent
an impression of misdiagnosis or inadequeate therapy