Superior Performance of Magnetic Nanoparticles for Entrapment and Fixation of Bovine Serum Albumin In-Vitro

BACKGROUND: In recent years, extensive studies have been performed on magnetite nanoparticles (MNPs) and their applications, which have shown the current project to be one of the major applications by laboratory results.METHODS: The nanoparticles synthesized in this project were deposited by the co-precipitation method, which structure was identified by analyzers such as SEM, FT-IR, and EDX. The aim of this project is the adsorption and fixation of biomolecule (BSA (bovine serum albumin) protein on the surface of magnetic nanoparticles.RESULTS: The adsorption results by electrophoresis and spectrophotometric analyzers showed an absorption rate above 55% ie; 55% of the protein is fixed on the MNPs nanoparticles. This absorption is due to the high level of functionality of magnetic nanoparticles for adsorption of protein. The results of the EDX analysis also show the possible electrostatic bonding between the nanoparticles and the protein, this is derived from –OH with –NH2 groups of the nanobiocompound (MNPs /protein). After bonding, the two are easily separated.CONCLUSION: In this project, the Fe3O4 nanoparticles was synthesized and identified by SEM, FT-IR, and EDX analyzers and finally reacted with the BSA protein (for the absorption of protein on MNPs) under experimental conditions at a standard temperature of 25° C. The results showed that about 55% of the protein was fixed on magnetic nanoparticles

High-Power and High-Performance Catalyst for Suzuki Coupling Reaction

In this project, the aim was to carry out the Suzuki reaction using a new and unique catalyst with a base of Fe3O4 magnetic nanoparticles coated using a new ligand. In fact, this magnetic catalyst has an inhomogeneous surface to create a connection between the organic and aqueous phases so that the carbon–carbon coupling reaction is completely performed on its large surface. The structure of this catalyst uses two metals, nickel and cobalt, which are coated on a bed of amino linkers and propel the Suzuki coupling reaction at high speed on the catalyst surface. The products obtained are from ideal and optimal conditions with an efficiency of over 98%. The catalyst has a recovery power of over 96% and has enough power to perform several coupling reactions several times. Lastly, the magnetic nanocatalyst is easily separated from the reaction medium by an external field and has 100% power when performing other reactions