84 research outputs found
Adult Ocular Toxocariasis Mimicking Ciliary Body Malignancy
Purpose. To discuss an unusual presentation of ocular toxocariasis. Methods. Case report. Results. A 40-year-old woman presented with decreased vision in the left eye with a long history of recurrent red eye from uveitis. Eosinophilia and positive ELISA titers for Toxocara canis favored the diagnosis of ocular toxocariasis. Over 3 months, an anterior scleral mass had a rapid growth raising the possibility of medulloepithelioma, which rarely can mimic uveitic syndromes. Surgical plan changed from local excision to enucleation. Histopathology demonstrated a large homogeneous mass of chronic inflammatory cells with inflammation of the overlying thinned out sclera, medial rectus insertion, and limbal cornea. The triad of peripheral granuloma, eosinophilia, and positive blood serology established the diagnosis of ocular toxocariasis. Conclusions. Ocular toxocariasis can mimic ocular malignancy such as medulloepithelioma in adults and rarely presents as an anterior scleral mass
American Society of Hematology 2021 guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19
Background: Coronavirus disease 2019 (COVID-19)-related critical illness and acute illness are associated with a risk of venous thromboembolism (VTE).Objective: These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians, and other health care professionals in decisions about the use of anticoagulation for thromboprophylaxis for patients with COVID-19-related critical illness and acute illness who do not have confirmed or suspected VTE.Methods: ASH formed a multidisciplinary guideline panel and applied strict management strategies to minimize potential bias from conflicts of interest. The panel included 3 patient representatives. The McMaster University GRADE Centre supported the guideline-development process, including performing systematic evidence reviews (up to 19 August 2020). The panel prioritized clinical questions and outcomes according to their importance for clinicians and patients. The panel used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach, including GRADE Evidence-to-Decision frameworks, to assess evidence and make recommendations, which were subject to public comment.Results: The panel agreed on 2 recommendations. The panel issued conditional recommendations in favor of prophylactic-intensity anticoagulation over intermediate-intensity or therapeutic-intensity anticoagulation for patients with COVID-19-related critical illness or acute illness who do not have confirmed or suspected VTE.Conclusions: These recommendations were based on very low certainty in the evidence, underscoring the need for high-quality, randomized controlled trials comparing different intensities of anticoagulation. They will be updated using a living recommendation approach as new evidence becomes available.Thrombosis and Hemostasi
American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: May 2021 update on the use of intermediate-intensity anticoagulation in critically ill patients
Background: COVID-19-related critical illness is associated with an increased risk of venous thromboembolism (VTE). Objective: These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians, and other health care professionals in making decisions about the use of anticoagulation for thromboprophylaxis in patients with COVID-19-related critical illness who do not have confirmed or suspected VTE.Methods: ASH formed a multidisciplinary guideline panel that included 3 patient representatives and applied strategies to minimize potential bias from conflicts of interest. The McMaster University Grading of Recommendations Assessment, Development and Evaluation (GRADE) Centre supported the guideline development process by performing systematic evidence reviews (up to 5 March 2021). The panel prioritized clinical questions and outcomes according to their importance for clinicians and patients. The panel used the GRADE approach to assess evidence and make recommendations, which were subject to public comment. This is an update on guidelines published in February 2021.Results: The panel agreed on 1 additional recommendation. The panel issued a conditional recommendation in favor of prophylactic-intensity over intermediate-intensity anticoagulation in patients with COVID-19-related critical illness who do not have confirmed or suspected VTE.Conclusions: This recommendation was based on low certainty in the evidence, which underscores the need for additional high-quality, randomized, controlled trials comparing different intensities of anticoagulation in critically ill patients. Other key research priorities include better evidence regarding predictors of thrombosis and bleeding risk in critically ill patients with COVID-19 and the impact of nonanticoagulant therapies (eg, antiviral agents, corticosteroids) on thrombotic risk.Thrombosis and Hemostasi
Measurement of correlated jet cross sections in collisions at TeV
We report on measurements of differential cross sections,
where the muon is from a semi-leptonic decay and the is
identified using precision track reconstruction in jets. The semi-differential
correlated cross sections, d/d\Et^{{\bar b}}, d/d\pt^{{\bar
b}}, and d/d for \pt^{\mu}>~9 GeV/c,
~10 GeV, ~1.5, are
presented and compared to next-to-leading order QCD calculations.Comment: Uses Latex, Article 12 point, figures appended as uuencoded file The
full PostScript available via WWW at
http://www-cdf.fnal.gov/physics/pub95/cdf3164_mu_bbar_prd_final.p
Measurement of the Meson Differential Cross Section, , in Collisions at TeV
This paper presents the first direct measurement of the meson
differential cross section, , in collisions at
TeV using a sample of pb accumulated by
the Collider Detector at Fermilab (CDF). The cross section is measured in the
central rapidity region GeV/ by fully
reconstructing the meson decays and , where and .
A comparison is made to the theoretical QCD prediction calculated at
next-to-leading order.Comment: 14 pages. Submitted to Phys. Rev. Lett. The postscript file is at
http://www-cdf.fnal.gov/physics/pub95/cdf2893_bexcl_xsection.p
Search for New Particles Decaying to Dijets in p-pbar Collisions at sqrt(s)=1.8 TeV
We have used 19 pb**-1 of data collected with the Collider Detector at
Fermilab to search for new particles decaying to dijets. We exclude at 95%
confidence level models containing the following new particles: axigluons with
mass between 200 and 870 GeV, excited quarks with mass between 80 and 570 GeV,
and color octet technirhos with mass between 320 and 480 GeV.Comment: Submitted to Physical Review Letters in December 199
The Charge Asymmetry in W-Boson Decays Produced in p-pbar Collisions at sqrt(s) = 1.8 TeV
The charge asymmetry has been measured using decays recorded by
the CDF detector during the 1992-93 run of the Tevatron Collider. The asymmetry
is sensitive to the ratio of and quark distributions to at
, where nonperturbative effects are minimal. It is found
that of the two current sets of parton distributions, those of Martin, Roberts
and Stirling (MRS) are favored over the sets most recently produced by the CTEQ
collaboration. The asymmetry data provide a stronger constraints on
ratio than the recent measurements of which are
limited by uncertainties originating from deutron corrections.Comment: to be published in PR
Measurement of and in collisions at TeV
We present a measurement of and in proton - antiproton collisions at TeV
using a significantly improved understanding of the integrated luminosity. The
data represent an integrated luminosity of 19.7 pb from the 1992-1993
run with the Collider Detector at Fermilab (CDF). We find ~nb and ~nb.Comment: Uses Latex, Article 12 point, figure appended as uuencoded file The
full PostScript available via WWW at
http://www-cdf.fnal.gov/physics/pub95/cdf3312_sigma_1a_prl_v3.p
Limits on and couplings from and production in collisions at TeV
Direct limits are set on and three-boson couplings in a
search for and production with high transverse momentum in
collisions at TeV, using the Collider Detector
at Fermilab. The results are in agreement with the SU(2) U(1) model of
electroweak interactions. Assuming Standard Model coupling, the the
limits are interpreted as direct evidence for a non-zero coupling at
subprocess energies near 500 GeV. Alternatively, assumiong identical and
couplings, bounds and are obtained at CL for a form factor scale 1000 GeV.Comment: 16 pages, submitted to PRL, URL:
http://www-cdf.fnal.gov/physics/pub95/cdf2951_vvprl.p
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