Relationship of coronary collateral development with mean arterial pressure in patients with stable coronary artery disease

Aim: The prognostic value of blood pressure and the association between these parameters and cardiovascular conditions have been established in literature. In this study, we aimed to investigate the correlation between peripheral blood pressure parameters with degree of coronary collateral development (CCD) in stable coronary artery disease (CAD) subjects with established critical artery stenosis. Methods: A total of 363 patients with stable angina pectoris undergoing coronary arteriography were enrolled and divided on the basis of the development of CCD into two groups: group with adequate CCD (n=120) and group with inadequate CCD (n=243). Peripheral blood pressure parameters were evaluated before coronary arteriography. Results: Peripheral diastolic blood pressure (DBP) and mean arterial pressure (MAP) levels were significantly higher in the inadequate CCC group (81.5±10.7 vs 77.9±9.9 p=0.02 and 100.6±11.8 vs 96.6±9.3 <.001). In Pearson’s correlation analysis revealed that, Peripheral DBP and MAP levels were significantly correlated with Rentrope Collateral Grading (r= 0.26, p<0.003 and r=0.29, p<0.001, respectively). ROC curve analysis of MAP and DBP for prediction of inadequate. At the cut-off value of > 99,8mmHG, sensitivity and specificity of MAP were 57% and 69%, respectively. At the cut-off value of >79,5 mmHg, sensitivity and specificity of DAP were 72% and 42%, respectively. Conclusion: The present study suggests that Peripheral DBP and MAP levels may be associated with degree of collateral development in chronic stable CAD. Low peripheral DBP and MAP in the case of severe coronary stenosis in stable CAD may be an important stimulus for coronary collateral development

Comparison of platelet volume indices in acute coronary syndrome

Aim: To compare the parameters showing the platelet volume index in unstable angina pectoris (USAP), non-ST elevation myocardial infarction (non-STEMI) and ST elevation myocardial infarction (STEMI). Methods: The platelet volume indices of 94 USAP, 161 non-STEMI and 86 STEMI cases with a total of 341 patients (245 men, 96 women) were compared. The patients between March 2015 and October 2018 who admitted to Bolu Abant İzzet Baysal University Hospital with the diagnosis of acute coronary syndrome were compared using platelet distribution width (PDW), PDW to platelet ratio (PPR), mean platelet volume (MPV), MPV to platelet ratio (MPR). Results: No significant difference was found between the 3 groups in terms of PDW (p = 0.26), PPR (p = 0.87), MPV (p = 0.41) and MPR (p = 0.78) values. Conclusion: In our study, there was no statistically significant difference between the types of acute coronary syndrome and platelet volume indices

Comparison of eosinophil counts in patients with acute pulmonary embolism: Could it be a predictor factor?

Aim: To investigate whether there is a relationship between both massive and sub-massive pulmonary embolism (PE) and eosinophil counts in order to evaluate it as a predictor factor. Methods: This retrospective study included 108 patients (64 sub-massive and 44 massive) who received both tomographic and clinical diagnoses of pulmonary embolism, and 75 subjects served as controls. Hemogram parameters were compared between patients with massive and sub-massive pulmonary embolism and those of control groups.Results: In terms of white blood cell and eosinophil counts, the lowest value was evident in the massive PE group whereas the control group had the highest value. The eosinophil counts increased significantly one week after the treatment when compared to those at the presentation with PE (0.112 (0.003-0.853) vs. (0.144 (0.011-0.914), p=0.01). Spearman correlation test showed a significant positive correlation between right ventricular dysfunction or elevated cardiac troponin level and massive PE (r=0.54, p <0.001), whereas a negative correlation was detected between eosinophil count and the presence of massive PE (r=-0.36, p<0.001). Conclusion: The results of our study suggest that lower eosinophil counts may lead a physician to suggest a higher probability of acute massive pulmonary embolism rather than sub-massive pulmonary embolism. However, further randomized studies are required to confirm these findings

Evaluation of electrocardiographic ventricular repolarization parameters in stable coronary artery disease

Aim: To examine the relationship between the SYNTAX score (SS) and cardiac repolarization parameters such as cQTd and Tp-e values, and Tp-e/QT, Tp-e/JT, Tp-e/QTc, and Tp-e/JTc ratios in patients who have stable angina pectoris. Methods: 12-lead resting electrocardiograms (ECGs) and SS of 160 patients (51 female and 109 male) undergoing coronary angiography with the pre-diagnosis of stable angina pectoris were evaluated. Patients with a SS below 22 were classified as Group 1 (low-SYNTAX), and those above 22 (high-SYNTAX) as Group 2. Forty-four patients with normal coronary angiography were included in Group 3. Results: Mean age of the patients was 62.4±9.1 years. The heart rate, QRS, QT, cQT and JT durations between the groups were similar. In addition, relatively recent ventricular repolarization indices such as Tp-e interval and Tp-e/QT, Tp-e/JT, Tp-e/QTc, and Tp-e/JTc ratios were also not substantially different between groups. Conclusion: Several surface ECG predictors of ventricular arrhythmias, including QTd, JT and Tp-e intervals and their ratios to QT and JT, are not significantly correlated with SYNTAX score-assessed CAD severity in patients with stable angina pectoris

Relationship of atherosclerosis and atrial fibrillation predictors with body composition in obese individuals

Aim: To investigate the markers that may predict both atrial fibrillation (AF) and atherosclerosis in obese patients. Method: This study was conducted on 108 participants (54 women and 54 men) with a body mass index (i.e., BMI) of at least 30. In addition to the electrocardiogram (ECG) and transthoracic echocardiography (TTE) findings, we also analyzed the findings of body composition by means of the bioelectric impedance analysis method using the Tanita MC 780 MA analyzer in all participants. Results: We found that the minimal area of the left atrium (LA) had a very strong (r = 0.978, p = 0.022) correlation with visceral adiposity and a weak positive correlation with waist circumference. Aortic stiffness had a weak positive correlation with visceral adiposity ratio (p = 0.022) and fat mass (r = 0.323, p = 0.001). The diameter of LA had weak positive correlations with visceral adiposity (p = 0.018), waist circumference (r = 0.336, p < 0.001), fat-free mass (r = 0.323, p = 0.001), muscle mass (r = 0.324, p = 0.001), liquid mass (r = 0.323, p = 0.001) and metabolic age (r = 0.364, p < 0.001). Again, we found weak positive correlations of epicardial fat tissue with visceral adiposity (r = 0.459, p = 0.018) and metabolic age (r = 0.350, p < 0.001). Conclusions: In our study, it has been noted that obese patients may have different levels of risk for AF and atherosclerosis, and there may be a more risky subgroup in which the distribution of some anthropometric and body tissue components differs

The role of baseline and post-treatment frontal QRS-T angle for detecting arterial blood pressure control

Objectives: In this study, we aimed to investigate the value of the frontal QRS-T angle (f(QRS-T)) in determining blood pressure control among newly diagnosed hypertensive patients with no left ventricular hypertrophy. Methods: Fifty patients with newly diagnosed hypertension were included in this single-center study. The patients were examined with 12-lead ECGs and 24-hour ambulatory blood pressure monitoring (24 h-ABPM) before and 1 month after antihypertensive treatment. Results: Baseline and post-treatment f(QRS-T) angle values were observed to be similar (38.0 [0.0–174.0] and 37.0 [1.0–139.0], respectively; p = .827). The values of QT minimum (p = .006), QTc mean (p = .030), Tp-e (p = .027), and JTc (p = .010) significantly decreased after control of blood pressure. Conclusions: The f(QRS-T) angle, which can be easily calculated on the ECG, is not a useful tool to determine hypertension control at early stage in newly diagnosed hypertensive patients

Is ionizing radiation a risk factor for anxiety in employees?

Kurtar Mansiroglu, Asli/0000-0002-1495-1697; sincer, isa/0000-0003-2399-9585; gunes, yilmaz/0000-0003-3817-851X; COSGUN, MEHMET/0000-0002-6965-7444WOS:000599837000016PubMed: 33331577OBJECTIVE: Workers describe many physical and mental symptoms when working in radiation areas. This study aimed to assess these symptoms in radiation workers using the Beck Anxiety Inventory (BAI). METHODS: A total of 42 radiation workers (22 males and 20 females, mean age 34 +/- 7 years) and 47 control subjects (22 males and 27 females, mean age 31 +/- 8 years) who work in non-radiation areas in the hospital were included in the study. All participants anonymously filled out the Beck Anxiety Inventory (BAI) questionnaire. RESULTS: The demographic data of workers were not significantly different between groups. In the BAI, the dizzy or lightheaded (p =0.01), terrified (p= 0.01), unsteady (p=0.02), heart-pounding and racing (p=0.02) items were significantly higher in the radiation-exposed group compared to the control group. vertical bar The BAI score was also significantly higher in the radiation-exposed group (11.1 +/- 6.8 vs. 8.7 +/- 3.8, p =0.04) CONCLUSION: These results suggest the possibility that radiation may play a role in the psychometric properties of workers. The effects of radiation on the health of employees need to be further investigated and understood