1,277 research outputs found

    On Factorization of a Special type of Vandermonde Rhotrix

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    Vandermonde matrices have important role in many branches of applied mathematics such as combinatorics, coding theory and cryptography. Some authors discuss Vandermonde rhotrices in the literature for its mathematical enrichment. Here, we introduce a special type of Vandermonde rhotrix and obtain its LR factorization, namely left and right triangular factorization which is further used to obtain the inverse of the rhotrix

    Detection of a-to-i rna editing in sars-cov-2

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    ADAR1-mediated deamination of adenosines in long double-stranded RNAs plays an important role in modulating the innate immune response. However, recent investigations based on metatranscriptomic samples of COVID-19 patients and SARS-COV-2-infected Vero cells have recovered contrasting findings. Using RNAseq data from time course experiments of infected human cell lines and transcriptome data from Vero cells and clinical samples, we prove that A-to-G changes observed in SARS-COV-2 genomes represent genuine RNA editing events, likely mediated by ADAR1. While the A-to-I editing rate is generally low, changes are distributed along the entire viral genome, are overrepresented in exonic regions, and are (in the majority of cases) nonsynonymous. The impact of RNA editing on virus–host interactions could be relevant to identify potential targets for therapeutic interventions

    On factorization of a special type of vandermonde rhotrix

    Get PDF
    Vandermonde matrices have important role in many branches of applied mathematics such as combinatorics, coding theory and cryptography. Some authors discuss the Vandermonde rhotrices in the literature for its mathematical enrichment. Here, we introduce a special type of Vandermonde rhotrix and obtain its LR factorization namely left and right triangular factorization, which is further used to obtain the inverse of the rhotrix

    Gravity in the 3+1-Split Formalism II: Self-Duality and the Emergence of the Gravitational Chern-Simons in the Boundary

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    We study self-duality in the context of the 3+1-split formalism of gravity with non-zero cosmological constant. Lorentzian self-dual configurations are conformally flat spacetimes and have boundary data determined by classical solutions of the three-dimensional gravitational Chern-Simons. For Euclidean self-dual configurations, the relationship between their boundary initial positions and initial velocity is also determined by the three-dimensional gravitational Chern-Simons. Our results imply that bulk self-dual configurations are holographically described by the gravitational Chern-Simons theory which can either viewed as a boundary generating functional or as a boundary effective action.Comment: 25 pages; v2: minor improvements, references adde
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