1,277 research outputs found
On Factorization of a Special type of Vandermonde Rhotrix
Vandermonde matrices have important role in many branches of applied mathematics such as combinatorics, coding theory and cryptography. Some authors discuss Vandermonde rhotrices in the literature for its mathematical enrichment. Here, we introduce a special type of Vandermonde rhotrix and obtain its LR factorization, namely left and right triangular factorization which is further used to obtain the inverse of the rhotrix
Detection of a-to-i rna editing in sars-cov-2
ADAR1-mediated deamination of adenosines in long double-stranded RNAs plays an important role in modulating the innate immune response. However, recent investigations based on metatranscriptomic samples of COVID-19 patients and SARS-COV-2-infected Vero cells have recovered contrasting findings. Using RNAseq data from time course experiments of infected human cell lines and transcriptome data from Vero cells and clinical samples, we prove that A-to-G changes observed in SARS-COV-2 genomes represent genuine RNA editing events, likely mediated by ADAR1. While the A-to-I editing rate is generally low, changes are distributed along the entire viral genome, are overrepresented in exonic regions, and are (in the majority of cases) nonsynonymous. The impact of RNA editing on virus–host interactions could be relevant to identify potential targets for therapeutic interventions
On factorization of a special type of vandermonde rhotrix
Vandermonde matrices have important role in many branches of applied mathematics such as combinatorics, coding theory and cryptography. Some authors discuss the Vandermonde rhotrices in the literature for its mathematical enrichment. Here, we introduce a special type of Vandermonde rhotrix and obtain its LR factorization namely left and right triangular factorization, which is further used to obtain the inverse of the rhotrix
Gravity in the 3+1-Split Formalism II: Self-Duality and the Emergence of the Gravitational Chern-Simons in the Boundary
We study self-duality in the context of the 3+1-split formalism of gravity
with non-zero cosmological constant. Lorentzian self-dual configurations are
conformally flat spacetimes and have boundary data determined by classical
solutions of the three-dimensional gravitational Chern-Simons. For Euclidean
self-dual configurations, the relationship between their boundary initial
positions and initial velocity is also determined by the three-dimensional
gravitational Chern-Simons. Our results imply that bulk self-dual
configurations are holographically described by the gravitational Chern-Simons
theory which can either viewed as a boundary generating functional or as a
boundary effective action.Comment: 25 pages; v2: minor improvements, references adde
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