OVM compliant verification for a wishbone compatible i2c master controller core

Increasing design complexity and concurrency of Integrated Circuits has made traditional directed testbenches an unworkable solution for testing. Today, testing as a word has been substituted with verification. Verification engineers have to ensure what goes to the factory for manufacturing is an accurate representation of the design specification. Inter Integrated Circuit (I2C) bus is a very widely used communication protocol in embedded system design due to its hardware simplicity and high data transfer rates capability. Most ICs incorporate I2C interface. Thus the ASIC design process of these ICs calls for robust, independent and exhaustive verification to reduce the risks of their failures. Open Verification Methodology (OVM) is an open source verification methodology library intended to run on multiple platforms and be supported by multiple EDA vendors. This thesis attempts to study and hence introduces a comprehensive verification environment for the latest specifications of the I2C bus protocol realized in the OVM platform, a new industry standard for comprehensive verification due to its rich base classes and OOP features. This work has been challenging since very few work has been reported in this domain for reference

Singlet-Doublet Self-interacting Dark Matter and Radiative Neutrino Mass

Self-interacting dark matter (SIDM) with a light mediator is a promising scenario to alleviate the small-scale problems of the cold dark matter paradigm while being consistent with the latter at large scales, as suggested by astrophysical observations. This, however, leads to an under-abundant SIDM relic due to large annihilation rates into mediator particles, often requiring an extension of the simplest thermal or non-thermal relic generation mechanism. In this work, we consider a singlet-doublet fermion dark matter scenario where the singlet fermion with a light scalar mediator gives rise to the velocity-dependent dark matter self-interaction through a Yukawa type attractive potential. The doublet fermion, by virtue of its tiny mixing with the singlet, can be long-lived and can provide a non-thermal contribution to the singlet relic at late epochs, filling the deficit in the thermal relic of singlet SIDM. The light scalar mediator, due to its mixing with the standard model Higgs, paves the path for detecting such SIDM at terrestrial laboratories leading to constraints on model parameters from CRESST-III and XENON1T experiments. Enlarging the dark sector particles by two more singlet fermions and one scalar doublet, all odd under an unbroken $\mathcal{Z}_2$ symmetry can also explain non-zero neutrino mass in scotogenic fashion.Comment: 17 pages, 16 captioned figures, Version accepted for publication in PR

Initial‐valued first‐order fuzzy differential equation in Bi‐level inventory model with fuzzy demand

In the present paper, two methods for the solution of an initial valued first ordered fuzzy differential equation are presented and applied in a fuzzy EOQ model. The constructed model is a bi‐level inventory problem involving wholesaler‐retailers‐customers. The wholesaler buys and sells the item instantaneously to several retailers. In the next level, the retailers sell the units to customers with a time dependent imprecise demand, which introduce the fuzzy nature in the differential equation. The selling price of the item is a step‐wise time dependent decreasing function. The fuzzy objectives are transformed into crisp one following fuzzy extension principle and centroid formula. The model is illustrated through Interactive Fuzzy Decision Making (IFDM) and Multi Objective Genetic Algorithm (MOGA) and the results from two methods are compared. First Published Online: 14 Oct 201

Diagnostic yield of cartridge based nucleic acid amplification test in Mycobacterium tuberculosis in a tertiary care medical college and hospital of Southern Odisha, India

Background: Tuberculosis is the ninth leading cause of death worldwide. India contributes to about one fifth of global TB burden. It is very important to diagnose early and treat tuberculosis to cut down transmission of tuberculosis.Methods: Author conducted a retrospective study in Department of Pulmonary Medicine SLN Medical College, Koraput, Odisha to analyze the utility and yield of CBNAAT. Study period was from April 2018 to March 2019. Inclusion criteria was all patients whose samples were subjected to CBNAAT were included in our study.  Sputum samples from pulmonary tuberculosis patients, and extra pulmonary samples (pleural fluid, ascitic fluid, CSF, synovial fluid and gastric lavage etc. were included in our study population. Exclusion criteria was patients who were under anti tubercular therapy for pulmonary, extra pulmonary and MDR TB were excluded from this study. Data were collected from Pulmonary Medicine Department, ART center, DOTS center and CBNAAT center. Total number of samples tested for CBNAAT, different sample collection sites, age and sex distribution of patients, HIV status of all patients, result of smear microscopy for AFB and CBNAAT and Rifampicin resistance status were analyzed.The detail statistical analysis was done in tabulation form.Results: A total of 2621 samples were tested in CBNAAT during the study period. Mean age of the study population was 38.03 years. 1881 tested were negative and 740 samples were positive for CBNAAT. Of these 2621 samples, 2526 were pulmonary samples (sputum, pleural fluid samples) and 95 were extra pulmonary samples. Author found rifampicin resistance rate of 0.54% (4/740)) in pulmonary tuberculosis cases. There was no rifampicin resistance detected in extra pulmonary samples. CBNAAT could identify 536 cases (23.2%) that were smear negative. Author found TB- HIV co-infection rate of 6.22%.Conclusions: CBNAAT is an important diagnostic modality especially in sputum negative patients for early diagnosis and treatment. In our study it detected Mycobacterium tuberculosis in 23.2% of patients with negative smear for microscopy. Rifampicin resistance rate detected was very low compared to other studies

Muon (g − 2) and XENON1T excess with boosted dark matter in L − L model

Motivated by the growing evidence for lepton flavour universality violation after the first results from Fermilab's muon (g−2) measurement, we revisit one of the most widely studied anomaly free extensions of the standard model namely, gauged Lμ−Lτ model, known to be providing a natural explanation for muon (g−2). We also incorporate the presence of dark matter (DM) in this model in order to explain the recently reported electron recoil excess by the XENON1T collaboration. We show that the same neutral gauge boson responsible for generating the required muon (g−2) can also mediate interactions between electron and dark fermions boosted by dark matter annihilation. The required DM annihilation rate into dark fermion require a hybrid setup of thermal and non-thermal mechanisms to generate DM relic density. The tightly constrained parameter space from all requirements remains sensitive to ongoing and near future experiments, keeping the scenario very predictive.

Self-interacting inelastic dark matter in the light of XENON1T excess

We propose a self-interacting inelastic dark matter (DM) scenario as a possible origin of the recently reported excess of electron recoil events by the XENON1T experiment. Two quasidegenerate Majorana fermion DM particles interact within themselves via a light hidden sector massive gauge boson and with the standard model particles via gauge kinetic mixing. We also consider an additional long-lived singlet scalar, which helps in realizing correct dark matter relic abundance via a hybrid setup comprising both freeze-in and freeze-out mechanisms. While being consistent with the required DM phenomenology along with sufficient self-interactions to address the small-scale issues of cold dark matter, the model with GeV-scale DM can explain the XENON1T excess via inelastic down-scattering of the heavier DM component into the lighter one. All these requirements leave a very tiny parameter space, keeping the model very predictive for near-future experiments. © 2021 authors

Boosted Self-Interacting Dark Matter and XENON1T Excess

We propose a self-interacting boosted dark matter (DM) scenario as a possible origin of the recently reported excess of electron recoil events by the XENON1T experiment. The Standard Model has been extended with two vector-like fermion singlets charged under a dark U(1)D gauge symmetry to describe the dark sector. While the presence of light vector boson mediator leads to sufficient DM self-interactions to address the small scale issues of cold dark matter, the model with GeV scale DM can explain the XENON1T excess via scattering of boosted DM component with electrons at the detector. The requirement of large annihilation rate of heavier DM into the lighter one for sufficient boosted DM flux leads to suppressed thermal relic abundance. A hybrid setup of thermal and non-thermal contribution from late decay of a scalar can lead to correct relic abundance. All these requirements leave a very tiny parameter space for sub-GeV DM keeping the model very predictive for near future experiments

Coexisting Pulmonary Tuberculosis and Mucormycosis in a Patient with Aplastic Anemia Post Allogenic Stem Cell Transplantation

Infections are the most common cause of morbidity and mortality in allogenic stem cell transplant recipients. Survival of the patient depends on the accurate diagnosis of the infectious agents and prompt and effective management of the infection alongwith maintenance of adequate immunosuppression post transplantation. We here reported a case of aplastic anemia who developed left upper lobe consolidation post allogenic stem cell transplantation and was found to have combined infection with tuberculosis and mucormycosis. This is the first case of combined infection with tuberculosis and mucormycosis reported in such a host, with a favourable outcom

Pulseless Right Upper Limb: An Unusual Manifestation of Invasive Pulmonary Aspergillosis in Acute Myeloid Leukemia

Abstract Aspergillus is the most common cause of fungal pneumonia in acute leukemia patients receiving chemotherapy or undergoing hematopoietic stem cell transplantation. Despite a high index of suspicion and prompt institution of specific antifungal therapy, it causes significant morbidity and mortality in patients with hematological malignancies. It has to be differentiated from mucormycosis because the treatment differs. Histological confirmation obtained by lung biopsy is ideal, but is difficult to obtain in those patients who often have thrombocytopenia. We report a case of acute megakaryoblastic leukemia with typical manifestations of invasive pulmonary aspergillosis who developed pulseless right arm due to invasion of the right subclavian artery. When total leucocyte counts recovered, patient also developed immune reconstitution inflammatory syndrome and massive pulmonary hemorrhage, which was managed by bronchial artery embolization