2 research outputs found
An efficient and straight forward strategy for the synthesis of enantiomerically pure (S)-1-benzyl-5-(alkyl/aryl amino) methyl)-pyrrolidin-2-ones
936-939A simple, efficient and straightforward strategy
for the synthesis of enantiomerically
pure (S)-5-((alkyl/aryl amino) methyl)-pyrrolidin-2-ones from N-benzyl-5(S)-pyroglutaminol through
Mitsunobu reaction has been described. These pyrrolidin-2-ones have great
potential to act as asymmetric precursors for the synthesis of bioactive compounds/ natural products requiring
suitably substituted aminomethyl group at C-5 of native
pyrrolidin-2-ones