Representative patterns of line probe assay (GenoType MTBDR-plus) strip.

<p>Lane 1, susceptible to rifampicin (RIF) and isoniazid (INH); Lane 2, MDR- TB (<i>rpoB</i> S531L mutation and<i>inhA</i> C15T mutation); Lane 3, rifampicin monoresistant (mutation at rpoB530–533 gene region); Lane 4, absence of TUB band; Lan 5, isoniazid monoresistant (<i>katG</i> S315T1 mutation); Lane 6, DNA positive control (sensitive to rifampicin and isoniazid); Lane 7, DNA negative control.</p

Performance of LPA test as compared to LJ DST in detecting resistance to rifampicin, isoniazid, and MDR-PTB in 242 smear positive sputum samples.

<p>MDR-PTB = multi-drug resistant pulmonary tuberculosis; NPV = negative predictive value; PPV = positive predictive value,(values in parantheses are with 95% confidence intervals); 27/269 samples did not have both phenotypic and genotypic results and hence were excluded.</p

Band patterns of drug resistant <i>Mycobacterium tuberculosis</i> strains using line probe assay.

<p>RIF = rifampicin; INH = isoniazid; MDR-PTB = multidrug resistant-pulmonary tuberculosis. Percentage values are shown in parentheses.</p