Location Tracking with Safe Paths and Safe Zones in Android

In this paper, we will present the process of tracking location with respect to set safe paths and safe zones in an android smartphone for an android smartphone. For the safety of women and children, using android phones, we have introduced the concept of safe paths and safe zones. The safe paths could be set for respective person, using the android smartphone, and the person’s location would be tracked against these safe paths. So, whenever the person is deviated from the safe path with a certain threshold, specified by the user, a notification or an alert is generated on the android smartphone indicating the deviation from specified safe path. Similarly, safe zones could be set so that whenever person enters or exits the safe zone an alert is generated on android smartphone

Natural Language Processing in Biomedical Literature for Analysing the Effects of Neurodynamic in Pain and Disability in Carpal Tunnel Syndrome

Carpal tunnel syndrome (CTS) a most common peripheral neuropathy characterised by numbness, tingling in the sensory distribution area of the of the median nerve, particularly in the thumb , index finger ,middle finger and radial side of ring finger along with motor weakness, distal to wrist that results into decreased hand grip strength and hand function disability. CTS puts an economy burden on healthcare services as its incidence and prevalence are increasing day by day although a slight decline in numbers has been seen over a period time. Fuzzy logic retains expert information in an intelligent system that may be effectively utilized by others, simulating the cognitive decision-making abilities of the specialist, and helping junior doctors with less expertise make better diagnoses. Therefore, the use of such an expert system is advised to speed up and enhance the accuracy of the diagnosis in patients with suspected CTS by studying different literatures. To device, evidence based therapeutic protocol from biomedical literature for the treatment of pain and disability in CTS. To analyse the effect of openers, sliders, and tensioners on NPRS and disability in carpal tunnel syndrome, using biomedical literature. Therefore, we draw the very encouraging conclusion that further research on the application of such a fuzzy expert system for medical opinion prediction and diagnosis is warranted

Study to assess the role of bromocriptine in treatment of diabetes mellitus

Background: Bromocriptine is a dopamine D2 receptor agonist and a sympatholytic agent used very frequently in treatment of hyperprolactinemia, Parkinsonism and acromegaly. Its quick release formulation has been approved for treatment of type 2 diabetes mellitus as an adjunct to diet and exercise. This study evaluated the antihyperglycemic effect of quick release bromocriptine in alloxan induced diabetic rats.Methods: 24 albino rats were taken and divided into four groups of six rats in each group. Diabetes was induced in three groups and one group was kept as a control group. After successful induction of diabetes, in remaining three group, first group was given no treatment second group was treated with bromocriptine and the third group was treated with metformin. Fasting blood sugar of all the groups were measured on day 1, 7, 14 and 28 of treatment.Results: In this study both the treatment groups were found to have significant (P<0.05) antihyperglycemic effect. Further studies are needed to evaluate and compare antihyperglycemic effect and safety profile of bromocriptine with established antidiabetic drugs.Conclusions: From this study, we concluded that individually both metformin and bromocriptine were effective in controlling hyperglycemia but metformin was better in achieving normal mean FBS. Further studies are required to ascertain the consistency in hypoglycemic effect of bromocriptine as well as its effect in lipid profile and cardiovascular outcomes. Study taking different doses of bromocriptine or with increasing the duration of study can elaborate its role in achieving proper glycemic control over time

Study of changes in serum lipid profile and blood sugar level by perindopril and telmisartan during treatment of systemic hypertension

Background: This study was designed to compare adverse effects on serum lipid profile and blood sugar level in the treatment with two commonly used drugs perindopril and telmisartan in cases of hypertension. This was an “observational” and “cross-sectional” study.Methods: A total of 100 patients were included in each, Groups A and B. In both groups, half the patients were given perindopril 4 mg OD and half were given telmisartan 40 mg OD for 24 weeks. Total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), triglycerides (TG), fasting blood sugar (FBS), and postprandial blood sugar (PPBS) level was estimated initially and then at 4th, 12th, and 24th week. Statistical analysis was done using ANOVA.Results: With perindopril initial means of TC, HDL, LDL, TGs, FBS, and PPBS in Groups A and B were 190.32, 49.76, 117.96, 165.04, 84.56, 122.60, and 188.80, 51.64, 118.52, 159.12, 93.92, 133.60, respectively. After 24 weeks, these values were 190.84, 50.68, 118.60, 163.84, 83.48, 120.20, and 190.96, 52.04, 118.28, 157.56, 93.96, 133.68, respectively (p > 0.05). With telmisartan, initial means of TC, HDL, LDL, TG, FBS, and PPBS in both groups were 188.08, 49.76, 118.84, 167.20, 83.72, 120.68, and 188.08, 46.88, 121.96, 167.84, 91.44, 131.72, respectively. After 24 weeks, these values in both groups were 189.36, 49.80, 120.04, 165.96, 82.60, 118.36 and 186.12, 45.28, 121.08, 167.72, 92.76, 129.56 respectively (p > 0.05).Conclusions: It concluded that both perindopril and telmisartan had not any significant adverse effects on plasma lipid profile and blood sugar level in both groups

Role of Uroflowmetry in Children with Ano-Rectal Malformation in Anticipating Upper Urinary Tract Damage

Background: The lower urinary tract dysfunction (LUTD) has high incidence in children with ano- rectal malformation (ARM) which if left untreated leads to upper tract damage.Aim: To determine role of uroflowmetry in early diagnosis of LUTD in children with ARM.Methods: This prospective study included twenty consecutive patients of ARM and every patient underwent uroflowmetry at-least 6 weeks after definitive procedure.Results: The mean age of patients was 3.015±0.86 years. Of the twenty patients, there were 12 (60%) males and 8 (40%) females; 11 (55%) were high ARM, 4 (20%) were intermediate and 5(25%) were low ARM. Lower urinary tract symptoms (LUTS) was present in 8/20 (40%) patients but uroflowmetric abnormalities were present in 11/20 (55%) patients. Forty five percent (5/11) patients with abnormal uroflowmetry were asymptomatic and 25% (2/8) symptomatic patients had normal uroflowmetry. The incidence of uroflowmetric abnormalities was significantly higher in patients with spinal anomalies (p=0.03; χ2=4.1) and those with high ARM (p=0.004; χ2=8.1).Conclusion: Uroflowmetry is a noninvasive method that may help in early detection of neurovesical dysfunction in asymptomatic children and subsequent cystometric analysis in patients with uroflowmetric abnormalities can be done for early definitive diagnosis and prevention of upper urinary tract damage