406 research outputs found
Assimilative Integration of Gestalt Therapy in the Treatment of Pentazocine Drug Dependence: A Case Report
Application of gestalt therapy is not common with Nigerian clients. The more common
psychotherapy modalities are the indigenous psychotherapy models of either Harmony
Restoration Therapy or Meseron Therapy. This paper presents a case report of Ms. J. E, a 28
year old single graduate, a civil servant. Client was misdiagnosed at the age of 24 years as
being anaemic while undergoing her National Youth Service Corps (NYSC) Scheme and was
placed on injectable Pentaxocine. Client became addicted to the drug, using it as a stimulant
when depressed. Client’s abuse of the drug led her to stealing personal belongings of family
members to purchase the drug. Client stole her mother’s gold trinkets worth about 5 million
Nairas, which purportedly led the mother developing kidney failure and her eventual death.
Client had gone for previous rehabilitation, which did not achieve positive result. Client was treated with gestalt therapy in order to resolve the unfinished business that she had with her mother. Client improved following treatment and is still stable after two years follow-up
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A post-processor for the PEST code
A new post-processor has been developed for use with output from the PEST tokamak stability code. It allows us to use quantities calculated by PEST and take better advantage of the physical picture of the plasma instability which they can provide. This will improve comparison with experimentally measured quantities as well as facilitate understanding of theoretical studies
Radial nerve neurotmesis in closed humeral shaft fracture: unusual case
Radial nerve neurotmesis constitutes a major problem in the treatment of closed fractures of the mid-shaft of the humerus. A case of radial nerve neurotmesis associated with a closed fracture of mid-shaft of the humerus is reported. Radial nerve neurotmesis was found at the fractured site. Early exploration of the nerve and primary internal fixation of the fracture was done which gave a satisfactory result
Characterization of a cotton interspecific hybrid of American cotton with wild species G. armourianum
Wild species constitute a source of valuable genes for many adverse climatic conditions, disease and pests. To match up the level of quick depleting insect pest and disease resistance and fast evolving pests, it is the urge of the hour to broaden the resistance base. In order to achieve this goal in cotton, wide hybridization was performed between G. hirsutum (AADD) cv. MCU5, CO14 and CO17, and G. armourianum and interspecific hybrids developed were characterized for several morphological characters for obtaining an idea about the status of the various traits. Interspecific hybrid developed with all three G. hirsutum varieties are potential lines for future introgression programs of insect and disease resistance along with other useful traits. The F1 hybrid displayed intermediate expression for most of the traits. Traits like colour of the stem, leaf colour, position of stigma, nectarines of hybrid completely resembled wild parent-and are considered as dominant in expression. The petal spot was present in the hybrid similar to that wild parent, unlike the cultivated parent; this appeared with different levels of intensity in F1 along with other characters like colour of the anther, and filament colour. Hybrids had profuse flowering throughout the year with low pollen load and pollen of variable shape and size expressing sterility to partial fertility. Noteworthy differentiation was seen between the leaf size and size of other plant parts of the hybrid
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Gyrokinetic Simulation of Global Turbulent Transport Properties in Tokamak Experiments
A general geometry gyro-kinetic model for particle simulation of plasma turbulence in tokamak experiments is described. It incorporates the comprehensive influence of noncircular cross section, realistic plasma profiles, plasma rotation, neoclassical (equilibrium) electric fields, and Coulomb collisions. An interesting result of global turbulence development in a shaped tokamak plasma is presented with regard to nonlinear turbulence spreading into the linearly stable region. The mutual interaction between turbulence and zonal flows in collisionless plasmas is studied with a focus on identifying possible nonlinear saturation mechanisms for zonal flows. A bursting temporal behavior with a period longer than the geodesic acoustic oscillation period is observed even in a collisionless system. Our simulation results suggest that the zonal flows can drive turbulence. However, this process is too weak to be an effective zonal flow saturation mechanism
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Simulations of beam-fueled supershot-like plasmas near ignition
Centrally peaked profiles would be advantageous for tokamak reactors since the pressure and the bootstrap current would be peaked in the regions of intense reactivity. We use the TRANSP plasma analysis code to investigate the feasibility of fueling with neutral beam injection. We show that for certain conditions, neutral beams with energies less than 120 keV can penetrate into the cores of plasmas that have a large thermonuclear yield and Q[sub DT] [approximately]10. This value of ODT is too small for an economical reactor if the neutral beam injection is the only fueling source. We give examples for several proposed compact prototype reactor designs
A high-performance computational workflow to accelerate GATK SNP detection across a 25-genome dataset
Background: Single-nucleotide polymorphisms (SNPs) are the most widely used form of molecular genetic variation studies. As reference genomes and resequencing data sets expand exponentially, tools must be in place to call SNPs at a similar pace. The genome analysis toolkit (GATK) is one of the most widely used SNP calling software tools publicly available, but unfortunately, high-performance computing versions of this tool have yet to become widely available and affordable. Results: Here we report an open-source high-performance computing genome variant calling workflow (HPC-GVCW) for GATK that can run on multiple computing platforms from supercomputers to desktop machines. We benchmarked HPC-GVCW on multiple crop species for performance and accuracy with comparable results with previously published reports (using GATK alone). Finally, we used HPC-GVCW in production mode to call SNPs on a “subpopulation aware” 16-genome rice reference panel with ~ 3000 resequenced rice accessions. The entire process took ~ 16 weeks and resulted in the identification of an average of 27.3 M SNPs/genome and the discovery of ~ 2.3 million novel SNPs that were not present in the flagship reference genome for rice (i.e., IRGSP RefSeq). Conclusions: This study developed an open-source pipeline (HPC-GVCW) to run GATK on HPC platforms, which significantly improved the speed at which SNPs can be called. The workflow is widely applicable as demonstrated successfully for four major crop species with genomes ranging in size from 400 Mb to 2.4 Gb. Using HPC-GVCW in production mode to call SNPs on a 25 multi-crop-reference genome data set produced over 1.1 billion SNPs that were publicly released for functional and breeding studies. For rice, many novel SNPs were identified and were found to reside within genes and open chromatin regions that are predicted to have functional consequences. Combined, our results demonstrate the usefulness of combining a high-performance SNP calling architecture solution with a subpopulation-aware reference genome panel for rapid SNP discovery and public deployment. © 2024, The Author(s).Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]
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