Lego – Building a European Concept of Functionality

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Publisher website: http://www.e-elgar.co.uk/Professor Maniatis contributed 50% to this chapter.Professor Maniatis contributed 50% to this chapter.DISCLAIMER: This material is copyright protected and for personal use only.Professor Maniatis contributed 50% to this chapter.Professor Maniatis contributed 50% to this chapter.In this timely book, expert contributors address this controversial issue and identify the various points at which names are shared

Whither European Trade Mark Law? Arsenal and Davidoff: The Creative Disorder Stage

Professor Maniatis focuses on recent case law of the European Court of Justice (ECJ) to illustrate the present disorderly state of European trade mark law. With the advent of the Community Trade Mark within the European Union, the ECJ is in the process of shaping a new body of trade mark precedent that will influence both national registration laws and future legislative developments in trade mark and unfair competition law. The author proposes that this new course should be guided by basic principles of trade mark law rather than by compromise between adverse historical and national systems. The Article gives a history of the legislative framework behind the Community Trade Mark to set up a discussion of the ECJ\u27s jurisprudence on trade mark law. Maniatis analyzes judicial treatment of relevant doctrines, including distinctiveness, graphic representation, functionality, likelihood of association, and mark reputation

Introduction and Expression of a Rabbit β-globin Gene in Mouse Fibroblasts

The cloned chromosomal rabbit ß-globin gene has been introduced into mouse fibroblasts by DNA-mediated gene transfer (transformation). In this report, we examine the expression of the rabbit gene in six independent transformants that contain from 1 to 20 copies of the cloned globin gene. Rabbit globin transcripts were detected in two of these transformants at steady-state concentrations of 5 and 2 copies per cell. The globin transcripts from one cell line are polyadenylylated and migrate as 9S RNA on methylmercury gels. These transcripts reflect correct processing of the two intervening sequences but lack 48 ± 5 nucleotides present at the 5' terminus of rabbit erythrocyte globin mRNA

A new type of CP symmetry, family replication and fermion mass hierarchies

We study a two-Higgs-doublet model with four generalised CP symmetries in the scalar sector. Electroweak symmetry breaking leads automatically to spontaneous breaking of two of them. We require that these four CP symmetries can be extended from the scalar sector to the full Lagrangian and call this requirement the principle of maximal CP invariance. The Yukawa interactions of the fermions are severely restricted by this requirement. In particular, a single fermion family cannot be coupled to the Higgs fields. For two fermion families, however, this is possible. Enforcing the absence of flavour-changing neutral currents, we find degenerate masses in both families or one family massless and one massive. In the latter case the Lagrangian is highly symmetric, with the mass hierarchy being generated by electroweak symmetry breaking. Adding a third family uncoupled to the Higgs fields and thus keeping it massless we get a model which gives a rough approximation of some features of the fermions observed in Nature. We discuss a number of predictions of the model which may be checked in future experiments at the LHC.Comment: 24 pages. Version published in EPJC. Minor changes as suggested by the refere

CP properties of symmetry-constrained two-Higgs-doublet models

The two-Higgs-doublet model can be constrained by imposing Higgs-family symmetries and/or generalized CP symmetries. It is known that there are only six independent classes of such symmetry-constrained models. We study the CP properties of all cases in the bilinear formalism. An exact symmetry implies CP conservation. We show that soft breaking of the symmetry can lead to spontaneous CP violation (CPV) in three of the classes.Comment: 14 pages, 2 tables, revised version adapted to the journal publicatio

NF-kappaB signaling pathways in mammalian and insect innate immunity

In this review, we discuss recent advances in understanding the signaling pathways in mammalian and Drosophila innate immunity, with emphasis on the mechanisms by which NF-kappaB/Rel family proteins are activated

Effective Two Higgs Doublets in Nonminimal Supersymmetric Models

The Higgs sectors of supersymmetric extensions of the Standard Model have two doublets in the minimal version (MSSM), and two doublets plus a singlet in two others: with (UMSSM) and without (NMSSM) an extra U(1)'. A very concise comparison of these three models is possible if we assume that the singlet has a somewhat larger breaking scale compared to the electroweak scale. In that case, the UMSSM and the NMSSM become effectively two-Higgs-doublet models (THDM), like the MSSM. As expected, the mass of the lightest CP-even neutral Higgs boson has an upper bound in each case. We find that in the NMSSM, this bound exceeds not very much that of the MSSM, unless tan(beta) is near one. However, the upper bound in the UMSSM may be substantially enhanced.Comment: 8 pages, 1 table, 3 figure