Quality Assurance in Education through Quality Circles – Global and Indian Context

Since Independence, the education, particularly the higher education in India has undergone a unique transformation from elitist to egalitarian group. There has been the expansion of higher education facilities in India since independence. We can see the expansion of higher education with increasing speed day by day in the context of globalization, liberalization and privatization. But a big question in front of us is whether the quality is ensured or not. It is saddening to note that 128 universities who got themselves accredited by the NAAC only 32 per cent could get ‘A’ or above level of rating while another 52 per cent of them could manage with ‘B’ or above grade. The remaining 16 per cent fall in grade ‘C’ or above. NAAC assessment further indicates that 68% of colleges are rated as ‘B’ while another 23% colleges is rated as ‘C’ grade; and only the remaining 9% are ‘A’ grade. Thus the quality assurance in higher education is the need of the hour

Work motivation of teachers : relationship with transformational and transactional leadership behavior of college principals

The strength of an educational system largely depends upon the quality of its teachers. It is a teacher who helps to transform an individual into a person of imagination, wisdom, human love and enlightenment, and institutions into lampposts of posterity, and the country into a learning society. The National Policy on Education (1986) has rightly remarked “The status of the teacher reflects the sociocultural ethos of a society; It is in this context that today a teacher occupies a unique and significant place in any society

CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer

The functional roles of SNPs within the 8q24 gene desert in the cancer phenotype are not yet well understood. Here, we report that CCAT2, a novel long noncoding RNA transcript (lncRNA) encompassing the rs6983267 SNP, is highly overexpressed in microsatellite-stable colorectal cancer and promotes tumor growth, metastasis, and chromosomal instability. We demonstrate that MYC, miR-17-5p, and miR-20a are up-regulated by CCAT2 through TCF7L2-mediated transcriptional regulation. We further identify the physical interaction between CCAT2 and TCF7L2 resulting in an enhancement of WNT signaling activity. We show that CCAT2 is itself a WNT downstream target, which suggests the existence of a feedback loop. Finally, we demonstrate that the SNP status affects CCAT2 expression and the risk allele G produces more CCAT2 transcript. Our results support a new mechanism of MYC and WNT regulation by the novel lncRNA CCAT2 in colorectal cancer pathogenesis, and provide an alternative explanation of the SNP-conferred cancer risk