Amino acid sequence elucidation of human acrosin-trypsin inhibitor (HUSI-II) reveals that Kazal-type proteinase inhibitors are structurally related to β-subunits of glycoprotein hormones

The amino acid sequence of the acrosin-trypsin inhibitor HUSI-II from human seminal plasma is presented which unequivocally identifies HUSI-II as being of Kazal-type. In addition, the HUSI-II sequence shows a striking similarity to the middle part of glycoprotein hormone β-subunits thus revealing a hitherto unknown structural and evolutionary relationship between Kazal-type inhibitors and glycoprotein hormone

Emission Optics of the Steigerwald Type Electron Gun

The emission optics of a Steigerwald type electron gun is re-examined. The virtual and real points of divergence, divergence angles and beam-widths of the electron beams at different telefocusing strength are measured in detail for first time . Two different Wehnelt cylinders are used to establish a contrasting viewpoint. The original `focusing' curves measured by Braucks are reconstructed and will be explained only through a `new' interpretation which is different from the conventional views. While the image of the emitting surface in front of the filament is indeed telefocused beyond the anode, the envelope of the beam does not `focus' as expected. A new model for the emission mechanism is established based on our results.Comment: 14 pages, 10 figure

Superior analyzer for raman spectra with high acceptance cone, resolution, transmission, and quantum efficiency, and strong background reduction

A Raman analyzer for analyzing light emitted from a Raman cell is provided that has a beam splitter configured to split the light emitted from the Raman cell into a first beam and a second beam. An atomic vapor filter can be used to filter a Raman scattered line from the first beam and a chopper system can periodically interrupt the first and second beams that are directed towards a photo detector, which can convert light from the first and second beams into an electrical signal. The signal output from the photo detector can optionally be amplified, digitized, Fourier filtered, and/or subjected to Fourier analysis.https://digitalcommons.mtu.edu/patents/1011/thumbnail.jp

Technique to discriminate against ambient and scattered laser light in Raman spectrometry

Raman scattering, while a powerful and versatile technique, relies of the detection of weak signals. Detecting the signal can be difficult if there is interference, especially if the interference comes from scattered stray light of the laser used to generate the Raman signal. Described here is a frequency modulation technique in combination with heterodyne detection that simultaneously rejects interference from ambient light as well as from scattered stray laser light. This provides a means to detect Raman signal and discriminate against scattered light without using an expensive and bulky spectrometer.Board of Regents, University of Texas Syste

Regionale Modellierung der Wasser- und Stickstoffdynamik als Entscheidungsunterstützung für die Reduktion des N-Eintrags: am Beispiel des Trinkwassertalsperrensystems Weida-Zeulenroda, Thüringen

Die Arbeit beschäftigt sich mit der modellhaften Darstellung des Wasser- und Stickstoffhaushaltes des Einzugsgebietes eines Trinkwassertalsperrensystems. Ziel hierbei war es, eine Ausweisung von Flächen durchzuführen, die zum Stickstoffeintrag in die Talsperre beitragen und bei denen stickstoffreduzierendes Landnutzungsmanagement besonders wirksam ist. Ein Schwerpunkt liegt dabei in der Berücksichtigung des landschaftlichen Kontexts der einzelnen Flächen, durch die Untersuchung der lateralen Prozesse. Hierzu wurden umfangreiche Gelände und Modellstudien durchgeführt. Der auf den Modellierungsergebnissen beruhende Einsatz, eines auf Künstlichen Neuronalen Netzten basierenden Verfahrens, ermöglichte die optimierte Flächenausweisung

Superior analyzer for raman spectra with high acceptance cone, resolution, transmission, and quantum efficiency, and strong background reduction

A Raman analyzer for analyzing light emitted from a Raman cell is provided that has a beam splitter configured to split the light emitted from the Raman cell into a first beam and a second beam. An atomic vapor filter can be used to filter a Raman scattered line from the first beam and a chopper system can periodically interrupt the first and second beams that are directed towards a photo detector, which can convert light from the first and second beams into an electrical signal. The signal output from the photo detector can optionally be amplified, digitized, Fourier filtered, and/or subjected to Fourier analysis.Board of Regents, University of Texas Syste

Towards Measuring and Quantifying the Comprehensibility of Process Models -- The Process Model Comprehension Framework

Process models constitute crucial artifacts in modern information systems and, hence, the proper comprehension of these models is of utmost importance in the utilization of such systems. Generally, process models are considered from two different perspectives: process modelers and readers. Both perspectives share similarities and differences in the comprehension of process models (e.g., diverse experiences when working with process models). The literature proposed many rules and guidelines to ensure a proper comprehension of process models for both perspectives. As a novel contribution in this context, this paper introduces the Process Model Comprehension Framework (PMCF) as a first step towards the measurement and quantification of the perspectives of process modelers and readers as well as the interaction of both regarding the comprehension of process models. Therefore, the PMCF describes an Evaluation Theory Tree based on the Communication Theory as well as the Conceptual Modeling Quality Framework and considers a total of 96 quality metrics in order to quantify process model comprehension. Furthermore, the PMCF was evaluated in a survey with 131 participants and has been implemented as well as applied successfully in a practical case study including 33 participants. To conclude, the PMCF allows for the identification of pitfalls and provides related information about how to assist process modelers as well as readers in order to foster and enable a proper comprehension of process models.Comment: 16 pages, 5 Figures, 1 Table, additional materials in appendi

Raman spectrometer

An improved Raman spectrometer is provided, having, in a preferred embodiment, a light source comprising an injection-locked laser diode array, a multipass cell to multiply the intensity of the light source, a dynamic gas sample focusing system, and an atomic vapor filter to remove the Rayleigh scattered light. The laser diode arrays are tuned to match an absorption band of the atomic vapor filter. The Raman scattered light passes virtually unattenuated through the filter to be recorded by a Fourier transform spectrometer or other spectrometer. This invention permits higher sensitivity and resolution than prior art Raman spectrometers, in particular permitting identification and measurement of Raman emissions that occur at low wave numbers. The light source of this invention can also be used in conjunction with optical notch filters and photodetectors to permit detection and measurement of preselected species in a sample.Board of Regents, University of Texas Syste

COP 21 can become a turning point towards sustainable energy systems : paper on behalf of the secretariat of the Club of Rome preparing for COP 21

Will climate change stay below the 2 degree target in the 21st century on the basis of the COP 21 results? Looking into challenges and opportunities, this paper answers: To stay below the global 2dt is neither a real choice for the world society nor for businesses and civil societies in specific countries. It is a global guideline, scientifically developed for global negotiations, which should be broken down to national interests and actors. Key questions concerning the energy sector from the perspective of national interests are how to create and sustain a momentum for the inevitable energy transition, how to encourage disruptive innovations, avoid lock in effects, enable rapid deployment of energy efficiency and renewable energies etc. Or in other words: how to get to a competitive, economically benign, inclusive, low carbon and risk minimising energy system. With this background the paper argues that "burden sharing" is a misleading perception of strong climate mitigation strategies. It is more realistic to talk about "benefit sharing", using the monetary benefits and co-benefits of climate mitigation (e.g. energy cost savings, revenues from CO2-tax or emission trading systems) to help vulnerable national and international actors to adapt to the unavoidable climate risks. It has to be demonstrated on country level that the technologies and policy mix of strong climate mitigation and risk-minimising actions are indeed "benefit sharing" strategies which should be chosen anyhow, even if there was no climate change. For China and Germany this paper includes basic findings supporting this view