Additional file 3: Figure S3. of Enhanced recruitment of genetically modified CX3CR1-positive human T cells into Fractalkine/CX3CL1 expressing tumors: importance of the chemokine gradient

Lymphocyte infiltration in the lungs of tumor-bearing mice after adoptive transfer. Flow cytometry analysis of T lymphocytes entrapped in the lungs of mice receiving adoptive transfer of CX3CR1-T cells or GFP-T cells (3 mice per group). (A) Proportion of CD3+ T lymphocytes among CD45+ cells in the disaggregated lungs from mice bearing RKO-Mock or RKO-CX3CL1 tumors. (B) Proportion of CD3+ T lymphocytes among CD45+ cells in the disaggregated lungs from mice bearing NCI-H630 tumors. (JPG 1661 kb

Additional file 2: Figure S2. of Enhanced recruitment of genetically modified CX3CR1-positive human T cells into Fractalkine/CX3CL1 expressing tumors: importance of the chemokine gradient

Transduction of human T lymphocytes with eGFP/CX3CR1-eGFP gene. (A) Population of CD3+ and of CD4+/CD8+ T cells post retroviral transduction of eGFP/CX3CR1 or -eGFP gene after 3 days of in vitro culture with hIL-2 medium. (JPG 1522 kb