11 research outputs found
Cancer incidence rates and trends among children and adolescents in Piedmont, 1967-2011
In the past, increases in childhood cancer incidence were reported in Europe and North America. The aim of this study is to show updated patterns of temporal behavior using data of the Childhood Cancer Registry of Piedmont (CCRP), a region with approximately 4.5 million inhabitants in North-West Italy. CCRP has been recording incident cases in children (0-14 years) since 1967 and in adolescents (15-19) since 2000. Time trends were estimated as annual percent change (APC) over the 1976-2011 period for children, and over 2000-2011 for both children and adolescents. CCRP registered 5020 incident cases from 1967 to 2011. Incidence rates were 157 per million person-years for children (1967-2011) and 282 for adolescents (2000-2011). From 1976-2011, increasing trends were observed in children for all neoplasms (APC 1.1, 95%CI: 0.8; 1.5) and for both embryonal and non-embryonal tumors: 1.1%, (0.5; 1.6) and 1.2%, (0.7; 1.6), respectively. Increases were observed in several tumor types, including leukemia, lymphoma, central nervous system tumors and neuroblastoma. In 2000-2011, incidence rates showed mostly non statistically significant variations and large variability. The observation of trends over a long period shows that the incidence of most tumors has increased, and this is only partially explained by diagnostic changes. Large rate variability hampers interpretation of trend patterns in short periods. Given that no satisfying explanation for the increases observed in the past was ever found, efforts must be made to understand and interpret this peculiar and still ununderstood pattern of childhood cancer incidence
Comment on Piscitelli et al. Hospitalizations in Pediatric and Adult Patients for All Cancer Type in Italy: The EPIKIT Study under the E.U. COHEIRS Project on Environment and Health. Int. J. Environ. Res. Public Health 2017, 14, 495
In the "Epikit study" [1], P. Piscitelli with 27 co-authors from 20 scientific institutions estimated the absolute number of hospital admissions for newly diagnosed cancer in people aged 0-19 in Italian provinces and regions in 2007-2011.[...]
Childhood Cancer Registry of Piedmont 1967–2011: Incidence rates in children and adolescents by single year of age.
<p>(Data for adolescents available from 2000).</p
Childhood Cancer Registry of Piedmont 1976–2011: Number of cases (n) and annual percent change (APC) with corresponding 95% confidence interval.
<p>Childhood Cancer Registry of Piedmont 1976–2011: Number of cases (n) and annual percent change (APC) with corresponding 95% confidence interval.</p
Childhood Cancer Registry of Piedmont 1967–2011: Incidence rates by age groups.
<p>Number of cases (n), incidence rates per million per year (rate) and male-to-female ratio (M/F).</p
Childhood Cancer Registry of Piedmont 1967–2011: Incidence rates in children and adolescents by 3 year periods.
<p>(Data for adolescents available from 2000).</p
Childhood Cancer Registry of Piedmont 1967–2011: Data quality indicators by calendar period.
<p>Total number of cases per period (N), cases (number and percentage) identified through death certificate only (DCO), microscopically verified (MV) cases, cases with ill-defined or unspecified site (ICD-10: C26, C39, C48, C76, C80), cases based on imaging only, by calendar period of registration.</p