Tradurre il giornalismo d'autore: le columnas di Almudena Grandes

Il presente elaborato si propone di approfondire la produzione di Almudena Grandes come columnista, ossia, il suo contributo nell’ambito del giornalismo d’opinione, attraverso l’analisi stilistica e contenutistica di un corpus di 40 columnas scritte dall’autrice per El País e la proposta di traduzione di tre articoli appartenenti al corpus. Infatti, mentre Almudena Grandes come romanziera è ampiamente conosciuta anche al di fuori della Spagna poiché tradotta in molte lingue, lo stesso non si può dire per la sua non meno meritevole produzione giornalistica. L’analisi pre-traduttiva degli articoli del corpus di cui si propone la traduzione per un’ipotetica pubblicazione sul settimanale Internazionale è stata realizzata sulla base del modello proposto da Christiane Nord nel 2012 e ha permesso di individuare i principali problemi di traduzione legati al giornalismo d’autore e le strategie più adatte alla risoluzione degli stessi

Wayfinding e navigazione: un prototipo di app mobile accessibile per percorsi indoor personalizzati

In questa tesi vengono presentati lo studio e la realizzazione di una applicazione accessibile per la navigazione indoor. Gli scopi di questo software, disponibile sia per device Android che per quelli iOS, sono molteplici e includono l'intenzione di migliorare l'accessibilità degli edifici pubblici mediante uno strumento a basso costo. I principi all'origine del lavoro sono l'inclusione di utenti con disabilità sia visive che motorie abilitando la navigazione turn-by-turn indoor per gli individui che spesso trovano negato l'accesso a questo genere di strumenti. Inoltre, trattandosi di navigazione in palazzi storici, il sistema si occupa anche della presentazione di informazioni turistico/culturali legate alla posizione dell'utilizzatore. L'autore di questa tesi ha, in seguito allo studio delle tecnologie, partecipato all'implementazione del sistema sia per gli aspetti tecnologici come la gestione del segnale dei beacon (tecnologia adottata per il progetto), che per la realizzazione delle interfacce e l'esecuzione di test di usabilità

Carel, Marion (dir.). 2012. Argumentation et polyphonie. De Saint Augustin à Robbe-Grillet (Paris : L’Harmattan)

Le titre de l’ouvrage fait surgir d’emblée une multitude de questions relatives à la démarche et aux finalités des études ici recueillies. La conjonction « et » que relie « argumentation » et « polyphonie »  isole-t-elle deux objets d’étude distincts ou suggère-t-elle plutôt que les phénomènes polyphoniques et argumentatifs seront traités conjointement ? Les noms du philosophe chrétien et du chef de file du Nouveau Roman sont-ils évoqués simplement pour préciser l’étendue chronologique couver..

Tradurre la sicurezza alimentare come elemento competitivo per l’internazionalizzazione. Traduzione del Manuale HACCP di Olitalia S.r.l.

This dissertation thesis has been written as a result of the project “Language Toolkit”, promoted by the Department of Interpretation and Translation of Forlì in collaboration with the Romagna Chamber of Commerce. The aim of the project is to act as a bridge between local companies and Specialized Translation students, fostering business internationalisation and creating new potential job opportunities. This dissertation describes the 300-hour internship carried out by the author at the Forlì-based company Olitalia S.r.l., which processes and markets a plethora of vegetable oils. The task assigned to the trainee is the translation into British English of the HACCP Plan of Olitalia. This thesis consists of five chapters aimed at describing and analysing in-depth the work carried out during the internship at Olitalia. The first chapter focuses on the description of the company, the food safety discipline and HACCP method. The second chapter outlines the level of internationalisation and digitalisation of small and medium-sized enterprises located in Emilia-Romagna and the role of translation in multilingual business communication. The third chapter provides a theoretical background of the main technologies for translation which can be used as a support for the internationalisation process. The fourth chapter shows the preparatory work performed before starting the translation, with a particular focus on Nord’s text analysis and all the resources created and used to translate the HACCP Plan. Finally, the fifth chapter describes al the macro-strategies and micro-strategies employed to carry out the translation

BoscoR: Extending R from the desktop to the Grid

In this paper, we describe a framework to execute R functions on remote resources from the desktop using Bosco. The R language is attractive to researchers because of its high level programming constructs which lower the barrier of entry for use. As the use of the R programming language in HPC and High Throughput Computing (HTC) has grown, so too has the need for parallel libraries in order to utilize computing resources. Bosco is middleware that uses common protocols to manage job submissions to a variety of remote computational platforms and resources. The researcher is able to control and monitor remote submission from their interactive R IDE, such as RStudio. Bosco is capable of managing many concurrent tasks submitted to remote resources while providing feedback to the interactive R environment. We will also show how this framework can be used to access national infrastructure such as the Open Science Grid. Through interviews with R users, and their feedback after using BoscoR, we learned how R users work and designed BoscoR to fit their needs. We incorporated their feedback to improve BoscoR by adding much needed features, such as remote package management. A key design goal was to have a flat learning curve in using BoscoR for any R user

CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype.

Pancreatic ductal adenocarcinoma (PDA) is the third leading cause of cancer-related deaths in the United States, whereas colorectal cancer is the third most common cancer. The RNA-binding protein HuR (ELAVL1) supports a pro-oncogenic network in gastrointestinal (GI) cancer cells through enhanced HuR expression. Using a publically available database, HuR expression levels were determined to be increased in primary PDA and colorectal cancer tumor cohorts as compared with normal pancreas and colon tissues, respectively. CRISPR/Cas9 technology was successfully used to delete the HuR gene in both PDA (MIA PaCa-2 and Hs 766T) and colorectal cancer (HCT116) cell lines. HuR deficiency has a mild phenotype

Brain-Derived Neurotrophic Factor and Stem Cell-Based Technologies in Huntington’s Disease Therapy

Neurodegenerative disorders, such as Huntington’s disease (HD), Alzheimer’s disease (AD), and Parkinson’s disease (PD), are characterized by changes in the levels and activities of neurotrophic factors (NTFs), such as brain-derived neurotrophic factor (BDNF). Gain-of-function and loss-of-function experiments demonstrate in fact the linkage between wild-type huntingtin (HTT) and gene transcription and intracellular transport of BDNF. In the present chapter, we will analyze the involvement of BDNF in HD and other neurodegenerative diseases. We will discuss the current BDNF technologies focusing on stem cell therapies that induce BDNF upregulation, for instance, the method of autologous mesenchymal stem cell (MSC) culturing in the presence of cocktail of BDNF inducers and factors (MSC/BDNF), genetic engineering of MSC and their use as a vector for BDNF gene delivery, and combined method of establishment of embryonic stem cell (ESC)-derived BDNF-overexpressing neural progenitors, which is still at the preclinical stage. Clinical trial that uses MSC/BDNF is already in course, while genetic engineering of MSC/BDNF is in perspective to treat adult and juvenile HD. The potential application of these technologies is beyond HD. Other neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases also can be further included in the list of clinical trials that use MSC/BDNF or even ESC/BDNF-overexpressing neural progenitors