Linkage Disequilibrium structure at the <i>CMA1</i> gene locus.

<p>Linkage Disequilibrium pattern (Heat Map) is represented by pairwise D′ values between SNPs with MAF>5% based on genotypes from HapMap (CEU population). r2 values (x100) calculated for each SNPs pair are given in the squares. Blank squares represent r2 values equal to 100. Rectangles are used to indicate Tagging SNPs.</p

<i>CMA1</i> polymorphisms and heart mass in patient with aortic stenosis.

<p>Association between haplotypes h1.ACAGGA (A) and h2.ATAGAG (B) in the <i>CMA1</i> gene and potentially functional polymorphisms rs1800875 (C) and rs1956923 (D) in the promoter region of <i>CMA1</i> gene and natural logarithm of LVM/BSA in patients with aortic stenosis. Values are means with the SEM indicated by error bars.</p

Association between tagging and potentially functional SNP in the CMA1 gene and natural logarithm of LVM/BSA.

<p>*Adjusted for gender, age, ejection fraction, maximal aortic gradient.</p>#<p>significance after correction for multiple comparisons: p<0.0125.</p

Demographic Characteristics and Echocardiographic Data for Patients With Aortic Stenosis.

<p>Demographic Characteristics and Echocardiographic Data for Patients With Aortic Stenosis.</p

Mean values of the echocardiographic parameters Based on rs1956923 Genotypes in males.

<p>*adjusted for age, ejection fraction, maximal aortic gradient,</p

Association between haplotypes in the CMA1 gene and natural logarithm of LVM/BSA.

<p>*Adjusted for gender, age, ejection fraction, maximal aortic gradient.</p>#<p>significance after correction for multiple comparisons: p<0.0125.</p