Gendered Impact of Caregiving Responsibilities on Tenure Track Faculty Parents’ Professional Lives

Navigating a career while raising a family can be challenging, especially for women in academia. In this study, we examine the ways in which professional life interruptions due to child caregiving (e.g., opportunities not offered, professional travel curtailed) affect pre- and post-tenure faculty members’ career satisfaction and retention. We also examine whether sharing caregiving responsibilities with a partner affected faculty members’ (particularly women’s) career outcomes. In a sample of 753 tenure track faculty parents employed at a large research-intensive university, results showed that as the number of professional life interruptions due to caregiving increased, faculty members experienced less career satisfaction and greater desire to leave their job. Pre-tenure women’s, but not pre-tenure men’s, career satisfaction and intention to stay were negatively affected when they experienced at least one professional life interference. Pre-tenure men’s desire to stay in their job and career satisfaction remained high, regardless of the number of professional life interferences they experienced. Sharing parenting responsibilities with a partner did not buffer the demands of caregiving on pre-tenure women’s career outcomes. Our work highlights the need to consider the varied ways in which caregiving affects faculty members’ careers, beyond markers such as publications, and how institutions can support early career stage women with family-friendly practices

Managing the Career Effects of Discrimination and Motherhood: The Role of Collegial Support for a Caregiving Policy at a Research-Intensive U.S. University

Implementing and encouraging use of policies aimed at creating an equitable higher education workplace for women academics can be challenging. Often, policy usage may be avoided due to stigma or fear of being seen as not committed to one’s workplace, especially for expectant mothers. In the present study, we examined how collegial support for using a tenure clock extension policy affects pre-tenure women’s career outcomes. Among pre-tenure women academics at a large research-intensive institution in the United States (N = 63) who took advantage of the tenure clock extension policy, perceptions of collegial support for using this policy were related to career satisfaction and workplace belonging. Collegial support was particularly beneficial to that half of the sample who had recently experienced gender-based job discrimination. We discuss the role that institutions can play to support early career stage women

Missed opportunities: Psychological ramifications of counterfactual thought in midlife women

Counterfactual thinking entails the process of imagining alternatives to reality—what might have been. The present study examines the frequency, content, and emotional and cognitive concomitants of counterfactual thinking about past missed opportunities in midlife women. At age 43, nearly two-thirds of the sample of educated adult women reported having missed certain opportunities at some time in their lives. Most of the counterfactual thoughts concerned missed opportunities for greater challenge in work. Emotional distress at age 33 did not predict later counterfactual thought. Instead, counterfactual thinking at age 43 was associated with concurrent emotional distress. However, acknowledging counterfactual thinking about the past was also associated with envisioning ways to change things for the better in the future. This suggests the possibility that the negative appraisal often entailed in counterfactual thinking may be associated with emotional distress in the short run but with motivational benefits in the long run, at least for middle-aged women.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44634/1/10804_2005_Article_BF02251257.pd

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570