The Effect Of Situational Leadership And Motivation On Employee Performance Mediated By Job Satisfaction (Case Study In The Pharmacy Industry)

This study aims to explore the effect of situational leadership and motivation on employee performance through the mediation of job satisfaction in the pharmaceutical industry. This study is a development of previous research that has been conducted in the banking industry. The contribution of this research is expected to have managerial implications in the pharmaceutical industry when a leader has a situational leadership style who can build communication, provide clear directions, and divide tasks among employees, and when employees have high motivation they can feel satisfied. work to improve performance. The sample of this research is employees who work in several pharmaceutical industries in the Bekasi industrial area, West Java. The sample criteria in this study were employees with more than 1 year of service, working in marketing, PPIC, logistics, and production with positions ranging from staff to supervisor. Respondents were selected proportionally using the purposive sampling method. Data was obtained through a questionnaire distributed online. Data analysis technique using Structural Equation Modeling (SEM) with LISREL. From the research conducted, there are findings that motivation does not have a positive effect on employee performance, however, motivation can have a positive effect on employee performance through a mediator variable, namely, job satisfaction

PENGARUH KONSENTRASI LOCUST BEAN GUM, pH MEDIA dan SUHU FERMENTASI TERHADAP PRODUKSI MANANASE DARI Bacillus subtillis ATCC 6633

Mannanase is a hydrolase enzyme that works by hydrolyzing the β- 1,4-manosidic bond between mannose and mannose. This enzyme has many uses in the pharmaceutical, pulp and paper, and bioethanol industries. Mannanase is obtained through a substrate containing many hemicelluloses such as galactomannan which is found in Locust Bean Gum. Potential sources of mannanase are microorganisms such as bacteria. Bacillus subtillis is a Gram-positive bacteria that produces the mannanolytic enzyme. The purpose of this study was to determine the effect of several factors on mannanase production such as substrate concentration, pH of media and fermentation temperature. The method used in this research is agar-well diffusion method. The tests were carried out in sequence starting from the variables of LBG concentration, media pH and the last fermentation temperature. This research was conducted in several steps, as follows: bacterial rejuvenation, making starter Bacillus subtilis ATCC 6633, making mannanase production media with various concentration, pH and fermentation temperature and mannanase activity test using Congo Red. The results showed that the mannanase activity emerged as a clear zone surrounding the bacterial colony. The diameter of the clear zone is converted to the mannanolytic index. The results showed that the most optimum mananolytic index was formed at LBG concentration 0.25% with mannanolytic index 2.89 ± 0.09. The most optimal mannanolytic index was formed at pH 7 with mannanolytic index 2,62 ± 0,04. The most optimal mannanolytic index was formed at 37oC fermentation temperature with a mannanolytic index of 2.62 ± 0.04